Caudal regression syndrome from radiology and clinical perspective: A case series and a proposed new integrated diagnostic algorithm.

放射学和临床角度的尾回归综合征 ： 病例系列和新的综合诊断算法。

• 发表时间: 2023 Jul
• 来源期刊: Radiol Case Rep
• DOI: 10.1016/j.radcr.2023.04.015
• PMID: 37235076
• 文章类型: Case Reports
• 作者列表: Purbasari U,Nazar H,Miraj F,Aprilia D,Widiani W,Suprihatin M,Eureka AN

关键词: Caudal Regression Syndrome; Diagnostic Algorithm; Maternal Diabetes; Sacral Agenesis; Vertebral Agenesis

Abstract

Caudal regression syndrome (CRS) is a rare inherited disorder associated with orthopedic deformities, as well as urological, anorectal, and spine malformations. We present 3 cases of CRS found in our hospital, along with the respective radiologic and clinical findings of the disease. With different problems and chief complaints from each case, we propose a diagnostic algorithm that can be used as a helpful tool in managing CRS. CRS is a complex and rare congenital disorder that affects multiple systems and can result in a range of malformations. The diagnostic algorithm proposed from our findings from 3 CRS cases is important to help healthcare providers identify the types of CRS and apply a more individualized approach to improve the quality of life for the patient.

摘要

尾回归综合征（CRS）是一种罕见的遗传性疾病，与骨科畸形有关，以及泌尿科，肛门直肠,脊椎畸形.我们介绍了在我们医院发现的3例CRS，以及该疾病的放射学和临床发现。每个案件都有不同的问题和主要投诉，我们提出了一种诊断算法，可以用作管理CRS的有用工具。CRS是一种复杂且罕见的先天性疾病，会影响多个系统，并可能导致一系列畸形。我们从3例CRS病例的发现中提出的诊断算法对于帮助医疗保健提供者识别CRS的类型并应用更个性化的方法来改善患者的生活质量非常重要。