Abstract：
BACKGROUND: Infection is the leading cause of multiple organ dysfunction syndrome (MODS) in the elderly. Red blood cell distribution width (RDW) was considered to be associated with many diseases. We aimed to explore whether RDW was associated with MODS in elderly infected patients.
METHODS: We retrospectively collected data from elderly patients (≥ 65 years old) with infection. In this study, we conducted a 1:3 case-control match based on age and gender and utilized binary Logistic regression to investigate the impact of variables such as RDW on MODS.
RESULTS: A total of 576 eligible patients were included in this study. RDW in the case group was significantly higher than that in control group (p < 0.001). Multivariate analysis found that RDW was an independent risk factor for MODS in elderly infected patients (OR = 1.397, 95% CI: 1.166-1.674, p < 0.001).
CONCLUSIONS: RDW was an independent risk factor for MODS in elderly patients with infection.
METHODS: We retrospectively collected data from elderly patients (≥ 65 years old) with infection. In this study, we conducted a 1:3 case-control match based on age and gender and utilized binary Logistic regression to investigate the impact of variables such as RDW on MODS.
RESULTS: A total of 576 eligible patients were included in this study. RDW in the case group was significantly higher than that in control group (p < 0.001). Multivariate analysis found that RDW was an independent risk factor for MODS in elderly infected patients (OR = 1.397, 95% CI: 1.166-1.674, p < 0.001).
CONCLUSIONS: RDW was an independent risk factor for MODS in elderly patients with infection.
摘要：
背景：感染是老年人多器官功能障碍综合征（MODS）的主要原因。红细胞分布宽度（RDW）被认为与许多疾病有关。我们旨在探讨RDW是否与老年感染患者的MODS相关。
方法：我们回顾性收集了感染的老年患者（≥65岁）的数据。在这项研究中,我们根据年龄和性别进行了1:3病例-对照匹配,并利用二元Logistic回归分析研究RDW等变量对MODS的影响.
结果：本研究共纳入576例符合条件的患者。病例组的RDW显著高于对照组(p<0.001)。多因素分析发现RDW是老年患者MODS的独立危险因素(OR=1.397,95%CI:1.166~1.674,p<0.001)。
结论：RDW是老年MODS合并感染的独立危险因素。
方法：我们回顾性收集了感染的老年患者（≥65岁）的数据。在这项研究中,我们根据年龄和性别进行了1:3病例-对照匹配,并利用二元Logistic回归分析研究RDW等变量对MODS的影响.
结果：本研究共纳入576例符合条件的患者。病例组的RDW显著高于对照组(p<0.001)。多因素分析发现RDW是老年患者MODS的独立危险因素(OR=1.397,95%CI:1.166~1.674,p<0.001)。
结论：RDW是老年MODS合并感染的独立危险因素。
