Abstract：
OBJECTIVE: To describe a case of congenital glaucoma in atiger (Panthera tigris).
METHODS: An 8-month-old intact female tiger wasreferred for suspected glaucoma of the right eye. The right eye was buphthalmicwith moderate episcleral injection, circumferential superficial cornealneovascularization, moderate corneal edema, and a fixed dilated pupil. Tapetalreflection was absent due to a mature cataract. Rebound tonometry under generalanesthesia revealed 70 mmHg and 21 mmHg in the right and left eye, respectively.
METHODS: A trans-conjunctival enucleation was performedand the globe was submitted for histopathology.
RESULTS: Histopathology revealed a thin sclera, amorphousmaterial contouring an imperforate and hypoplastic iridocorneal angle, ahypoplastic lens with severe anterior-posterior compression, subcapsularepithelial hyperplasia, and Morganian globules, and segmental moderate retinalatrophy. Periodic acid-Schiff stain highlighted segmental dilations of theDescemet\'s membrane. Masson trichrome stain highlighted a pre-irido collagenmembrane.
CONCLUSIONS: The tiger\'s age and histopathologic findingsare consistent with congenital goniodysgenesis. This is the first known reportof congenital glaucoma in a tiger.
METHODS: An 8-month-old intact female tiger wasreferred for suspected glaucoma of the right eye. The right eye was buphthalmicwith moderate episcleral injection, circumferential superficial cornealneovascularization, moderate corneal edema, and a fixed dilated pupil. Tapetalreflection was absent due to a mature cataract. Rebound tonometry under generalanesthesia revealed 70 mmHg and 21 mmHg in the right and left eye, respectively.
METHODS: A trans-conjunctival enucleation was performedand the globe was submitted for histopathology.
RESULTS: Histopathology revealed a thin sclera, amorphousmaterial contouring an imperforate and hypoplastic iridocorneal angle, ahypoplastic lens with severe anterior-posterior compression, subcapsularepithelial hyperplasia, and Morganian globules, and segmental moderate retinalatrophy. Periodic acid-Schiff stain highlighted segmental dilations of theDescemet\'s membrane. Masson trichrome stain highlighted a pre-irido collagenmembrane.
CONCLUSIONS: The tiger\'s age and histopathologic findingsare consistent with congenital goniodysgenesis. This is the first known reportof congenital glaucoma in a tiger.
摘要：
目的：描述一例先天性青光眼患者（Pantheratigris）。
方法：一只8个月大的完整雌虎因怀疑右眼青光眼而转诊。右眼是布替米克和中度巩膜上注射，周围浅表角膜新生血管形成，中度角膜水肿，和一个固定的扩大瞳孔。由于成熟的白内障，没有反射。全身麻醉下的回弹眼压测定显示右眼和左眼分别为70mmHg和21mmHg，分别。
方法：进行经结膜摘除术，并对眼球进行组织病理学检查。
结果：组织病理学显示巩膜薄，形成无孔和发育不良的虹膜角膜角的无定形材料，发育不良晶状体严重的前后压缩，包膜下上皮增生，和摩根球，和节段性中度视网膜萎缩。周期性酸性希夫染色突出了Descemet膜的分段扩张。Masson三色染色突出了前虹膜胶原膜。
结论：老虎的年龄和组织病理学结果与先天性性腺发育是一致的。这是老虎先天性青光眼的第一个已知报告。
方法：一只8个月大的完整雌虎因怀疑右眼青光眼而转诊。右眼是布替米克和中度巩膜上注射，周围浅表角膜新生血管形成，中度角膜水肿，和一个固定的扩大瞳孔。由于成熟的白内障，没有反射。全身麻醉下的回弹眼压测定显示右眼和左眼分别为70mmHg和21mmHg，分别。
方法：进行经结膜摘除术，并对眼球进行组织病理学检查。
结果：组织病理学显示巩膜薄，形成无孔和发育不良的虹膜角膜角的无定形材料，发育不良晶状体严重的前后压缩，包膜下上皮增生，和摩根球，和节段性中度视网膜萎缩。周期性酸性希夫染色突出了Descemet膜的分段扩张。Masson三色染色突出了前虹膜胶原膜。
结论：老虎的年龄和组织病理学结果与先天性性腺发育是一致的。这是老虎先天性青光眼的第一个已知报告。
