关键词: SARS-CoV-2 Takotsubo syndrome extracorporeal membrane oxygenation transthoracic echocardiography

Mesh : Male Humans Middle Aged Shock, Cardiogenic / diagnostic imaging etiology therapy Takotsubo Cardiomyopathy / diagnosis diagnostic imaging Extracorporeal Membrane Oxygenation / adverse effects COVID-19 / complications Stroke Volume Ventricular Function, Left SARS-CoV-2 Echocardiography COVID-19 Testing

来  源:   DOI:10.1111/echo.15594

Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mainly invades the respiratory system, but may also cause various cardiovascular complications. We report a rare case of myocarditis associated with SARS-CoV-2 infection. A 61-year-old man was admitted to the hospital with a positive nucleic acid test for SARS-CoV-2. A sudden increase in troponin level (up to .144 ng/mL) was observed on the 8th day after admission. He developed symptoms of heart failure and progressed rapidly to cardiogenic shock. Echocardiography on the same day showed reduced left ventricular ejection fraction, reduced cardiac output, and segmental ventricular wall motion abnormalities. Takotsubo cardiomyopathy associated with SARS-CoV-2 infection was considered based on the typical echocardiography findings. We immediately started veno-arterial extracorporeal membrane oxygenation (VA-ECMO) treatment. The patient was successfully withdrawn from VA-ECMO after 8 days following recovery of ejection fraction to 65% and all indicators qualifying the withdrawal criteria. Echocardiography plays an important role in dynamic monitoring of cardiac changes in such cases and can help determine the timing of extracorporeal membrane oxygenation treatment and withdrawal.
摘要:
严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)主要侵入呼吸系统,但也可能引起各种心血管并发症。我们报告了与SARS-CoV-2感染相关的罕见心肌炎病例。一名61岁的男子因SARS-CoV-2核酸检测呈阳性而入院。入院后第8天观察到肌钙蛋白水平突然增加(高达.144ng/mL)。他出现了心力衰竭的症状,并迅速发展为心源性休克。当天超声心动图显示左心室射血分数降低,心输出量减少,和节段性室壁运动异常。根据典型的超声心动图检查结果,考虑了与SARS-CoV-2感染相关的Takotsubo心肌病。我们立即开始静脉动脉体外膜氧合(VA-ECMO)治疗。在射血分数恢复至65%且所有指标符合退出标准后8天后,患者成功退出VA-ECMO。超声心动图在动态监测此类情况下的心脏变化中起着重要作用,可以帮助确定体外膜氧合治疗和停药的时机。
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