关键词: case report external resorption human periodontal ligament stem cells maxillary defect tooth transplantation

来  源:   DOI:10.1097/MS9.0000000000000475   PDF(Pubmed)

Abstract:
Autologous tooth transplantation is the transplantation of an erupted, partially erupted, or unerupted tooth from one site to another in an individual. This is expected to maintain alveolar bone volume through physiological stimulation of the periodontal ligament (PDL). Tooth transplantation can be used for the closure of oroantral communication. As a simple, useful, and minimally invasive method, it should be considered a surgical option when a donor tooth is available in indicated cases. Herein, the authors report the case of a 20-year-old female patient whose left permanent maxillary first molar had to be extracted due to a longitudinal fracture and radicular cyst in the maxillary sinus floor. After the extraction, tooth 28 was exposed through an osteotomy and positioned in the gap. Nineteen years later, the autologous grafted tooth 28 could no longer be retained due to massive external resorption and was replaced by an implant. Human PDL stem cells can differentiate into bone-, fiber-, and cementum-forming cells and have the potential to build a PDL complex. Therefore, care must be taken to avoid damaging the PDL of the donor tooth during extraction. Autotransplanted teeth are expected to retain the alveolar bone volume. This case demonstrates the use of a transplanted tooth 28 for the treatment of a maxillary defect caused by the extraction of tooth 26 and removal of a radicular cyst. External resorption and regeneration of the bone of the maxillary sinus floor around the transplanted tooth occurred after 19 years.
摘要:
自体牙移植是指长出牙的移植,部分爆发,或从一个部位到另一个部位的未萌出的牙齿。预计这将通过牙周韧带(PDL)的生理刺激来维持牙槽骨体积。牙移植可用于口窦通信的闭合。作为一个简单的,有用的,和微创方法,当在指定的情况下可以使用供体牙齿时,应将其视为手术选择。在这里,作者报告了一例20岁的女性患者,由于上颌窦底的纵向骨折和根性囊肿,必须摘除左侧永久性上颌第一磨牙。提取后,牙齿28通过截骨术暴露并定位在间隙中。十九年后,由于大量的外部再吸收,自体移植的牙齿28不再能够保留,并被植入物取代。人类PDL干细胞可以分化为骨骼,纤维-,和牙骨质形成细胞,并有可能建立PDL复合物。因此,必须注意避免在拔牙期间损坏供体牙齿的PDL。自体移植的牙齿有望保留牙槽骨体积。该病例证明了使用移植的牙齿28来治疗由拔除牙齿26和去除神经根囊肿引起的上颌缺损。19年后,移植牙周围上颌窦底骨的外部吸收和再生发生。
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