PDF(Pubmed)
Abstract：
We present a patient who presented with diabetic ketoacidosis and severe rhabdomyolysis-induced acute kidney injury. The patient developed generalized edema, nausea, and vomiting, and his kidney function deteriorated, necessitating renal replacement therapy, despite the successful treatment of his initial conditions. A comprehensive evaluation was conducted to determine the underlying cause of the severe rhabdomyolysis, including autoimmune myopathies, viral infections, and metabolic disorders. A muscle biopsy revealed necrosis and myophagocytosis but no significant inflammation or myositis. The patient\'s clinical and laboratory results improved with appropriate treatment, including temporary dialysis and erythropoietin therapy, and he was discharged to continue his rehabilitation with home health care.
摘要：
我们介绍了一名患有糖尿病酮症酸中毒和严重横纹肌溶解引起的急性肾损伤的患者。患者出现全身性水肿,恶心,呕吐,他的肾功能恶化了,需要肾脏替代疗法，尽管他的初始条件得到了成功的治疗。进行了综合评估，以确定严重横纹肌溶解症的根本原因。包括自身免疫性肌病,病毒感染,和代谢紊乱。肌肉活检显示坏死和吞噬作用，但无明显的炎症或肌炎。通过适当的治疗，患者的临床和实验室结果得到改善，包括临时透析和促红细胞生成素治疗,他已经出院，继续接受家庭保健康复。
