A blinded assessor randomly assigned 24 participants with electrodiagnostically-confirmed mild or moderate CTS to either rPMS or conventional therapy. Both groups were briefed on disease progression and tendon-gliding exercises. In the intervention group, the rPMS protocol, five sessions of rPMS-with a frequency of 10 Hz, 10 pulses/train, and 100 trains/session-were performed over a period of 2 weeks, with three sessions in the first week and two sessions in the second week. At baseline and the end of the second week, the Boston Carpal Tunnel Questionnaire, pinch strength, and electrodiagnostic results were evaluated.
The rPMS group demonstrated significantly greater within-group improvement in symptom severity scores (2.3 vs. 1.6, p = 0.009) and pinch strength (10.6 lbs vs. 13.8 lbs, p < 0.001). Regarding electrodiagnostic parameters, sensory nerve action potential (SNAP) amplitude was significantly increased (8.7 µV vs. 14.3 µV, p = 0.002) within the group treated with rPMS. With conventional therapy, there were no statistically significant within-group differences. Multiple linear regression models showed that there were no significant differences in other outcomes in between-group comparisons.
Five sessions of rPMS resulted in significant reduction in symptom severity, improvement in pinch strength and increase in SNAP amplitude. Future research should investigate the clinical utility of rPMS using a larger sample and longer treatment and follow-up durations.
■一名盲法评估员随机分配了24名电诊断证实为轻度或中度CTS的参与者进行rPMS或常规治疗。两组都简要介绍了疾病进展和肌腱滑翔运动。在干预组中,rPMS协议,频率为10Hz的五个rPMS会话,10个脉冲/列,100列火车/会议-在2周内进行,第一周三次,第二周两次。在基线和第二周结束时,波士顿腕骨隧道调查问卷,夹紧强度,和电诊断结果进行了评估。
■rPMS组在症状严重程度评分方面表现出明显更大的组内改善(2.3vs.1.6,p=0.009)和夹紧强度(10.6磅vs.13.8磅,p<0.001)。关于电诊断参数,感觉神经动作电位(SNAP)振幅显着增加(8.7µVvs.14.3µV,p=0.002)在rPMS治疗组中。通过常规治疗,组间差异无统计学意义.多元线性回归模型显示,在组间比较中,其他结果没有显着差异。
■五次rPMS导致症状严重程度显着降低,改善捏合强度和增加SNAP振幅。未来的研究应该使用更大的样本和更长的治疗和随访持续时间来研究rPMS的临床实用性。