Abstract：
The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. This is the first guideline on the diagnosis and treatment of active Charcot neuro-osteoarthropathy in persons with diabetes published by the IWGDF. We followed the GRADE Methodology to devise clinical questions in the PACO (Population, Assessment, Comparison, Outcome) and PICO (Population, Intervention, Comparison, Outcome) format, conducted a systematic review of the medical literature, and developed recommendations with the rationale. The recommendations are based on the evidence from our systematic review, expert opinion when evidence was not available, and also taking into account weighing of the benefits and harms, patient preferences, feasibility and applicability, and costs related to an intervention. We here present the 2023 Guidelines on the diagnosis and treatment of active Charcot neuro-osteoarthropathy in persons with diabetes mellitus and also suggest key future topics of research.
摘要：
国际糖尿病足工作组（IWGDF）自1999年以来发布了关于糖尿病足病预防和管理的循证指南。这是IWGDF发表的关于糖尿病患者活动性Charcot神经骨关节病的诊断和治疗的第一个指南。我们遵循GRADE方法论来设计PACO中的临床问题(人口，评估,比较,结果)和PICO(人口，干预,比较,结果)格式，对医学文献进行了系统的回顾，并提出了有理由的建议。这些建议是基于我们系统审查的证据，没有证据时的专家意见，并考虑到利弊的权衡，患者偏好,可行性和适用性，以及与干预相关的成本。我们在此介绍2023年糖尿病患者活动性Charcot神经骨关节病的诊断和治疗指南，并提出了未来的关键研究主题。
