PDF(Pubmed)
Abstract：
BACKGROUND: Bell\'s palsy is an idiopathic facial palsy with an unknown cause, and 75% of patients heal spontaneously. However, the other 25% of patients continue experiencing mild or severe disabilities, resulting in a reduced quality of life. Currently, various treatment methods have been developed to treat this disease. However, there is controversy regarding their effectiveness, and new alternative treatments are needed.
METHODS: The patient suffered from left-sided facial paralysis due to Bell\'s palsy for 7 years. The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment. After follow-up for 32 mo, the paralysis was cured, and there was no recurrence.
CONCLUSIONS: Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell\'s palsy who do not spontaneously recover.
METHODS: The patient suffered from left-sided facial paralysis due to Bell\'s palsy for 7 years. The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment. After follow-up for 32 mo, the paralysis was cured, and there was no recurrence.
CONCLUSIONS: Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell\'s palsy who do not spontaneously recover.
摘要：
背景：贝尔麻痹是一种原因不明的特发性面神经麻痹，75%的患者自愈。然而,另外25%的患者继续经历轻度或重度残疾，导致生活质量下降。目前,已经开发了各种治疗方法来治疗这种疾病。然而,它们的有效性存在争议，需要新的替代疗法。
方法：患者因贝尔氏麻痹而出现左侧面瘫7年。患者接受了8次未培养的脐带间充质干细胞移植治疗。经过32个月的随访，瘫痪被治愈了,而且没有复发.
结论：未培养的脐带间充质干细胞移植可能是无法自发恢复的贝尔麻痹患者的潜在治疗方法。
方法：患者因贝尔氏麻痹而出现左侧面瘫7年。患者接受了8次未培养的脐带间充质干细胞移植治疗。经过32个月的随访，瘫痪被治愈了,而且没有复发.
结论：未培养的脐带间充质干细胞移植可能是无法自发恢复的贝尔麻痹患者的潜在治疗方法。
