PDF(Pubmed)
Abstract：
Eosinophilic fasciitis (EF), also known as Shulman syndrome, is a rare scleroderma-like disorder that is characterized by an acute onset of induration, swelling, erythema, and tenderness of the skin and deep fascia, often affecting all four limbs. We report a case of eosinophilic fasciitis in a 51-year-old female patient, whose diagnosis of EF was made based on the findings from clinical evaluation and magnetic resonance imaging (MRI) but without skin biopsy. She was treated with a combination therapy of prednisolone and methotrexate, and her response to therapy was assessed via clinical assessment and MRI. MRI may be a useful non-invasive diagnostic tool for not only supporting but also confirming the clinical diagnosis of EF when a skin-to-muscle biopsy is not available or cannot be performed, as well as for monitoring disease activity and response to therapy. Further prospective studies should be conducted to evaluate the precise sensitivity and specificity of MRI in diagnosing EF and also to create more structured protocols to guide the diagnosis and management of EF.
摘要：
嗜酸性筋膜炎(EF),也被称为舒尔曼综合症，是一种罕见的硬皮病样疾病，其特征是硬结的急性发作，肿胀,红斑,皮肤和深筋膜的压痛，经常影响四肢。我们报告了一例51岁女性患者的嗜酸性筋膜炎，他们的EF诊断是根据临床评估和磁共振成像（MRI）的结果做出的，但没有皮肤活检。她接受了泼尼松龙和甲氨蝶呤的联合治疗，通过临床评估和MRI评估患者对治疗的反应.MRI可能是一种有用的非侵入性诊断工具，不仅支持而且在无法进行皮肤到肌肉活检或无法进行时确认EF的临床诊断。以及监测疾病活动和对治疗的反应。应进行进一步的前瞻性研究，以评估MRI诊断EF的精确敏感性和特异性，并创建更结构化的方案来指导EF的诊断和管理。
