PDF(Pubmed)
Abstract：
Paraganglioma is a rare type of neuroendocrine tumor with variable clinical presentations, making diagnosis relatively challenging. In this report, we present a case of retroperitoneal paraganglioma in a patient who experienced intermittent episodes of dizziness and chest pain. Imaging studies conducted during the patient\'s hospitalization revealed the presence of a lesion in the upper region of the right kidney, as well as a mass in the left retroperitoneal area that was suspected to be a paraganglioma. Biochemical studies were collected, including 24-hour urine metanephrines, urine catecholamines, urine cortisol, plasma metanephrines, renin, and aldosterone. However, it took an extended period of time for these results to come back. Given high clinical suspicion, alpha-blockade was initiated without a definite diagnosis of paraganglioma. Ultimately, the patient underwent tumor resection and the final pathology confirmed paraganglioma. The pathology of the contralateral renal mass showed oncocytoma. This case serves as an illustration of the difficulties that can arise when diagnosing and treating undiagnosed paragangliomas within a community healthcare setting.
摘要：
副神经节瘤是一种罕见的神经内分泌肿瘤，临床表现各不相同，诊断相对具有挑战性。在这份报告中,我们介绍了一例腹膜后副神经节瘤的患者，该患者经历了间歇性的头晕和胸痛。在患者住院期间进行的影像学检查显示右肾上部存在病变，以及左侧腹膜后区域的肿块，怀疑是副神经节瘤。收集了生化研究，包括24小时尿液中的肾上腺素,尿儿茶酚胺,尿皮质醇,血浆间肾上腺素，肾素,还有醛固酮.然而,这些结果花了很长时间才回来。鉴于临床高度怀疑，在未明确诊断副神经节瘤的情况下开始α-阻断.最终,患者接受了肿瘤切除术，最终病理证实为副神经节瘤。对侧肾脏肿块的病理显示为嗜酸细胞瘤。该病例说明了在社区医疗保健环境中诊断和治疗未诊断的副神经节瘤时可能出现的困难。
