PDF(Pubmed)
Abstract：
UNASSIGNED: The goal of human papillomavirus (HPV) vaccination is the decline of HPV related premalignant lesions, leading to prevention of cervical cancer. Vaccination against HPV is recommended until the age of 45 to prevent viral reinfections and reactivations. The aim of this study was to evaluate adhesion to HPV vaccination and their associated factors in adult women.
UNASSIGNED: Cross-sectional study in two tertiary hospitals, with a questionnaire distributed to women born between 1974 and 1992, from September till November 2019. Data collected included sociodemographic information, clinical information, knowledge about HPV, and the HPV vaccine and data regarding vaccine recommendation. Factors associated with vaccination were searched by bivariate and multivariate statistical analysis.
UNASSIGNED: In 469 questionnaires, 25.4% (n = 119) women were vaccinated. The main reason for not vaccinating was the non-recommendation (n = 276; 70.2%). In bivariate analyses, vaccinated women were younger, predominantly not married, had higher educational level, and higher careers (P ≤ .001); an abnormal cytology, HPV infection or previous excision of the transformation zone were associated with a 3 to 4-fold increase in the odds of vaccination. Age, high-risk HPV infection, and knowing someone vaccinated remained factors independently associated with HPV vaccination in the multivariate analyses (P< .05). The recommendation of \"vaccinate immediately\" was independently associated with effectively doing it (P< .001).
UNASSIGNED: HPV vaccination is associated with vaccine recommendation, especially if it is recommended to do immediately. These results reinforce the need of health professionals to be aware of the impact that their recommendation has on adhesion to HPV vaccination.
UNASSIGNED: Cross-sectional study in two tertiary hospitals, with a questionnaire distributed to women born between 1974 and 1992, from September till November 2019. Data collected included sociodemographic information, clinical information, knowledge about HPV, and the HPV vaccine and data regarding vaccine recommendation. Factors associated with vaccination were searched by bivariate and multivariate statistical analysis.
UNASSIGNED: In 469 questionnaires, 25.4% (n = 119) women were vaccinated. The main reason for not vaccinating was the non-recommendation (n = 276; 70.2%). In bivariate analyses, vaccinated women were younger, predominantly not married, had higher educational level, and higher careers (P ≤ .001); an abnormal cytology, HPV infection or previous excision of the transformation zone were associated with a 3 to 4-fold increase in the odds of vaccination. Age, high-risk HPV infection, and knowing someone vaccinated remained factors independently associated with HPV vaccination in the multivariate analyses (P< .05). The recommendation of \"vaccinate immediately\" was independently associated with effectively doing it (P< .001).
UNASSIGNED: HPV vaccination is associated with vaccine recommendation, especially if it is recommended to do immediately. These results reinforce the need of health professionals to be aware of the impact that their recommendation has on adhesion to HPV vaccination.
摘要：
■人乳头瘤病毒（HPV）疫苗接种的目标是减少与HPV相关的癌前病变，导致预防宫颈癌。建议在45岁之前接种HPV疫苗，以防止病毒再感染和再激活。这项研究的目的是评估成年女性HPV疫苗接种的粘附性及其相关因素。
■两家三级医院的横断面研究，问卷分发给1974年至1992年之间出生的女性，从9月到2019年11月。收集的数据包括社会人口统计信息，临床信息，关于HPV的知识，以及HPV疫苗和有关疫苗推荐的数据。通过双变量和多变量统计分析搜索与疫苗接种相关的因素。
■在469份问卷中，25.4%(n=119)的妇女接种了疫苗。未接种疫苗的主要原因是未推荐（n=276；70.2%）。在双变量分析中，接种疫苗的妇女更年轻，主要是没有结婚,有较高的教育水平，和更高的职业（P≤0.001）；细胞学异常，HPV感染或先前切除转化区与疫苗接种几率增加3至4倍相关。年龄,高危型HPV感染,在多变量分析中，知道有人接种疫苗仍然是与HPV疫苗接种独立相关的因素（P<0.05）。“立即接种疫苗”的建议与有效接种独立相关（P<.001）。
■HPV疫苗接种与疫苗推荐相关，特别是如果建议立即做。这些结果加强了卫生专业人员的需求，以了解他们的建议对HPV疫苗接种粘附的影响。
■两家三级医院的横断面研究，问卷分发给1974年至1992年之间出生的女性，从9月到2019年11月。收集的数据包括社会人口统计信息，临床信息，关于HPV的知识，以及HPV疫苗和有关疫苗推荐的数据。通过双变量和多变量统计分析搜索与疫苗接种相关的因素。
■在469份问卷中，25.4%(n=119)的妇女接种了疫苗。未接种疫苗的主要原因是未推荐（n=276；70.2%）。在双变量分析中，接种疫苗的妇女更年轻，主要是没有结婚,有较高的教育水平，和更高的职业（P≤0.001）；细胞学异常，HPV感染或先前切除转化区与疫苗接种几率增加3至4倍相关。年龄,高危型HPV感染,在多变量分析中，知道有人接种疫苗仍然是与HPV疫苗接种独立相关的因素（P<0.05）。“立即接种疫苗”的建议与有效接种独立相关（P<.001）。
■HPV疫苗接种与疫苗推荐相关，特别是如果建议立即做。这些结果加强了卫生专业人员的需求，以了解他们的建议对HPV疫苗接种粘附的影响。
