Abstract：
Onychomycosis is a fungal infection of the fingernails and toenails. In Europe, tinea unguium is mainly caused by dermatophytes. The diagnostic workup comprises microscopic examination, culture and/or molecular testing (nail scrapings). Local treatment with antifungal nail polish is recommended for mild or moderate nail infections. In case of moderate to severe onychomycosis, oral treatment is recommended (in the absence of contraindications). Treatment should consist of topical and systemic agents. The aim of this update of the German S1 guideline is to simplify the selection and implementation of appropriate diagnostics and treatment. The guideline was based on current international guidelines and the results of a literature review conducted by the experts of the guideline committee. This multidisciplinary committee consisted of representatives from the German Society of Dermatology (DDG), the German-Speaking Mycological Society (DMykG), the Association of German Dermatologists (BVDD), the German Society for Hygiene and Microbiology (DGHM), the German Society of Pediatric and Adolescent Medicine (DGKJ), the Working Group for Pediatric Dermatology (APD) and the German Society for Pediatric Infectious Diseases (DGPI). The Division of Evidence-based Medicine (dEBM) provided methodological assistance. The guideline was approved by the participating medical societies following a comprehensive internal and external review.
摘要：
甲癣是指指甲和脚趾甲的真菌感染。在欧洲,癣主要由皮肤癣菌引起。诊断检查包括显微镜检查，培养和/或分子测试（指甲刮片）。对于轻度或中度指甲感染，建议使用抗真菌指甲油进行局部治疗。在中度至重度甲癣的情况下，建议口服治疗（在没有禁忌症的情况下）。治疗应包括局部和全身药物。德国S1指南更新的目的是简化适当诊断和治疗的选择和实施。该指南基于当前的国际指南和指南委员会专家进行的文献综述的结果。这个多学科委员会由德国皮肤病学会（DDG）的代表组成，德语真菌学协会（DMykG），德国皮肤科医师协会（BVDD），德国卫生和微生物学会（DGHM），德国儿科和青少年医学学会（DGKJ），儿科皮肤病学工作组（APD）和德国儿科传染病学会（DGPI）。循证医学部（dEBM）提供了方法学援助。经过全面的内部和外部审查，该指南得到了参与医学协会的批准。
