PDF(Pubmed)
Abstract：
BACKGROUND: To compare the efficacy and safety of standard percutaneous nephrolithotomy (PCNL) with mini- PCNL for kidney stones 2-4 cm.
METHODS: Eighty patients were enrolled in a comparative study, they were randomly divided into mini-PCNL group (n = 40) and standard-PCNL (n = 40). Demographic characteristics, perioperative events, complications, stone free rate (SFR) were reported.
RESULTS: Both groups showed no significant difference in clinical data about age, stone location, back pressure changes, and body mass index. The mean operative time was (95 ± 17.9 min) in mini-PCNL, and (72.1 ± 14.9 min). Stone free rate were 80% and 85% in mini-PCNL and standard-PCNL respectively. Intra-operative complications, post-operative need for analgesia, hospital stay were significantly higher in standard-PCNL compared to mini-PCNL (85% vs. 80%). The study followed CONSORT 2010 guidelines for reporting parallel group randomization.
CONCLUSIONS: Mini-PCNL is an effective and safe treatment of kidney stones 2-4 cm, it has the advantage over standard-PCNL being has less intra-operative events, less post-operative analgesia, shorter hospital stay, while operative time and stone free rate are comparable when considering multiplicity, hardness, and site of stones.
METHODS: Eighty patients were enrolled in a comparative study, they were randomly divided into mini-PCNL group (n = 40) and standard-PCNL (n = 40). Demographic characteristics, perioperative events, complications, stone free rate (SFR) were reported.
RESULTS: Both groups showed no significant difference in clinical data about age, stone location, back pressure changes, and body mass index. The mean operative time was (95 ± 17.9 min) in mini-PCNL, and (72.1 ± 14.9 min). Stone free rate were 80% and 85% in mini-PCNL and standard-PCNL respectively. Intra-operative complications, post-operative need for analgesia, hospital stay were significantly higher in standard-PCNL compared to mini-PCNL (85% vs. 80%). The study followed CONSORT 2010 guidelines for reporting parallel group randomization.
CONCLUSIONS: Mini-PCNL is an effective and safe treatment of kidney stones 2-4 cm, it has the advantage over standard-PCNL being has less intra-operative events, less post-operative analgesia, shorter hospital stay, while operative time and stone free rate are comparable when considering multiplicity, hardness, and site of stones.
摘要：
背景：比较标准经皮肾镜取石术（PCNL）与微型PCNL治疗2-4cm肾结石的疗效和安全性。
方法：80名患者被纳入一项比较研究，随机分为微型PCNL组(n=40)和标准PCNL组(n=40)。人口特征，围手术期事件，并发症,报告无结石率（SFR）。
结果：两组在年龄、石头位置,背压变化,和体重指数。微型PCNL的平均手术时间为（95±17.9分钟），和（72.1±14.9分钟）。微型PCNL和标准PCNL的无结石率分别为80%和85%。术中并发症,术后需要镇痛，标准PCNL的住院时间明显高于迷你PCNL(85%vs.80%)。本研究遵循CONSORT2010报告平行组随机化的指南。
结论：Mini-PCNL是2-4cm肾结石的有效和安全的治疗方法，与标准PCNL相比，它具有术中事件较少的优势，术后镇痛较少，住院时间缩短,当考虑多重性时，手术时间和无结石率是相当的，硬度,和石头的地方。
方法：80名患者被纳入一项比较研究，随机分为微型PCNL组(n=40)和标准PCNL组(n=40)。人口特征，围手术期事件，并发症,报告无结石率（SFR）。
结果：两组在年龄、石头位置,背压变化,和体重指数。微型PCNL的平均手术时间为（95±17.9分钟），和（72.1±14.9分钟）。微型PCNL和标准PCNL的无结石率分别为80%和85%。术中并发症,术后需要镇痛，标准PCNL的住院时间明显高于迷你PCNL(85%vs.80%)。本研究遵循CONSORT2010报告平行组随机化的指南。
结论：Mini-PCNL是2-4cm肾结石的有效和安全的治疗方法，与标准PCNL相比，它具有术中事件较少的优势，术后镇痛较少，住院时间缩短,当考虑多重性时，手术时间和无结石率是相当的，硬度,和石头的地方。
