PDF(Pubmed)
Abstract：
Vertebra plana is a rare radiologic condition characterized by a uniform loss of height of a vertebral body that represents a diagnostic challenge for surgeons. The purpose of this study was to review all possible differential diagnoses that may present with a vertebra plana (VP) described in the current literature. For that purpose, we performed a narrative literature review in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, analyzing 602 articles. Patient demographics, clinical presentation, imaging characteristics and diagnoses were investigated. VP is not a pathognomonic feature of Langerhans cell histiocytosis, but other oncologic and non-oncologic conditions should be considered. The list of differential diagnoses, based on our literature review, can be recalled with the mnemonic HEIGHT OF HOMO: H-Histiocytosis; E-Ewing\'s sarcoma; I-Infection; G-Giant cell tumor; H-Hematologic neoplasms; T-Tuberculosis; O-Osteogenesis imperfecta; F-Fracture; H-Hemangioma; O-Osteoblastoma; M-Metastasis; O-Osteomyelitis, chronic.
摘要：
椎骨平面是一种罕见的放射学疾病，其特征是椎体高度的均匀损失，这对外科医生构成了诊断挑战。这项研究的目的是回顾当前文献中描述的可能存在椎骨平面（VP）的所有可能的鉴别诊断。为此,我们根据系统评价和荟萃分析指南的首选报告项目进行了叙述性文献综述，分析602篇文章。患者人口统计学，临床表现,研究了影像学特征和诊断。VP不是朗格汉斯细胞组织细胞增生症的病理特征，但其他肿瘤和非肿瘤条件应考虑。鉴别诊断列表，根据我们的文献综述，可以记忆高度HOMO：H-组织细胞增生症;E-Ewing肉瘤;I-感染;G-巨细胞瘤;H-血液肿瘤;T-结核;O-成骨不全症;F-骨折;H-血管瘤;O-骨母细胞瘤;M-转移;O-骨髓炎,慢性。
