关键词: cerebral aneurysm coil embolization microcatheter shaping treatment outcome virtual simulation

来  源:   DOI:10.3389/fneur.2023.1095266   PDF(Pubmed)

Abstract:
UNASSIGNED: The shaping of an accurate and stable microcatheter plays a vital role in the successful embolization of intracranial aneurysms. Our study aimed to investigate the application and the role of AneuShape™ software in microcatheter shaping for intracranial aneurysm embolization.
UNASSIGNED: From January 2021 to June 2022, 105 patients with single unruptured intracranial aneurysms were retrospectively analyzed with or without AneuShape™ software to assist in microcatheter shaping. The rates of microcatheter accessibility, accurate positioning, and stability for shaping were analyzed. During the operation, fluoroscopy duration, radiation dose, immediate postoperative angiography, and procedure-related complications were evaluated.
UNASSIGNED: Compared to the manual group, aneurysm-coiling procedures involving the AneuShape™ software exhibited superior results. The use of the software resulted in a lower rate of reshaping microcatheters (21.82 vs. 44.00%, p = 0.015) and higher rates of accessibility (81.82 vs. 58.00%, p = 0.008), better positioning (85.45 vs. 64.00%, p = 0.011), and higher stability (83.64 vs. 62.00%, p = 0.012). The software group also required more coils for both small (<7 mm) and large (≥7 mm) aneurysms compared to the manual group (3.50 ± 0.19 vs. 2.78 ± 0.11, p = 0.008 and 8.22 ± 0.36 vs. 6.00 ± 1.00, p = 0.081, respectively). In addition, the software group achieved better complete or approximately complete aneurysm obliteration (87.27 vs. 66.00%, p = 0.010) and had a lower procedure-related complication rate (3.60 vs. 12.00%, p = 0.107). Without this software, the operation had a longer intervention duration (34.31 ± 6.51 vs. 23.87 ± 6.98 min, p < 0.001) and a higher radiation dose (750.50 ± 177.81 vs. 563.53 ± 195.46 mGy, p < 0.001).
UNASSIGNED: Software-based microcatheter shaping techniques can assist in the precise shaping of microcatheters, reduce operating time and radiation dose, improve embolization density, and facilitate more stable and efficient intracranial aneurysm embolization.
摘要:
准确,稳定的微导管的成型在颅内动脉瘤的成功栓塞中起着至关重要的作用。我们的研究旨在探讨AneuShape™软件在颅内动脉瘤栓塞的微导管成形中的应用和作用。
从2021年1月至2022年6月,对105例单发未破裂颅内动脉瘤的患者进行了回顾性分析,无论是否使用AneuShape™软件来协助微导管成形。微导管可接近率,准确定位,并对成形稳定性进行了分析。在操作过程中,透视持续时间,辐射剂量,术后即刻血管造影,并对手术相关并发症进行评估。
与手册组相比,涉及AneuShape™软件的动脉瘤卷绕程序表现出优异的结果。使用该软件可降低微导管的整形率(21.82vs.44.00%,p=0.015)和更高的可及性率(81.82与58.00%,p=0.008),更好的定位(85.45vs.64.00%,p=0.011),和更高的稳定性(83.64vs.62.00%,p=0.012)。与手动组相比,软件组对于小(<7mm)和大(≥7mm)动脉瘤也需要更多的线圈(3.50±0.19vs.2.78±0.11,p=0.008和8.22±0.36vs.6.00±1.00,p=0.081)。此外,软件组实现了更好的完全或大约完全的动脉瘤闭塞(87.27vs.66.00%,p=0.010),并且具有较低的手术相关并发症发生率(3.60vs.12.00%,p=0.107)。没有这个软件,手术干预时间较长(34.31±6.51vs.23.87±6.98min,p<0.001)和更高的辐射剂量(750.50±177.81vs.563.53±195.46mGy,p<0.001)。
基于软件的微导管成形技术可以帮助微导管的精确成形,减少操作时间和辐射剂量,提高栓塞密度,并促进更稳定和有效的颅内动脉瘤栓塞。
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