PDF(Pubmed)
Abstract：
Optical coherence tomography angiography (OCT-A) is a valuable imaging technique, allowing non-invasive, depth-resolved, motion-contrast, high-resolution images of both retinal and choroidal vascular networks. The imaging capabilities of OCT-A have enhanced our understanding of the retinal and choroidal alterations that occur in inherited retinal diseases (IRDs), a group of clinically and genetically heterogeneous disorders that may be complicated by several vascular conditions requiring a prompt diagnosis. In this review, we aimed to comprehensively summarize all clinical applications of OCT-A in the diagnosis and management of IRDs, highlighting significant vascular findings on retinitis pigmentosa, Stargardt disease, choroideremia, Best disease and other less common forms of retinal dystrophies. All advantages and limitations of this novel imaging modality will be also discussed.
摘要：
光学相干断层扫描血管造影(OCT-A)是一种有价值的成像技术,允许非侵入性，深度解决，运动对比，视网膜和脉络膜血管网络的高分辨率图像。OCT-A的成像功能增强了我们对遗传性视网膜疾病（IRD）中发生的视网膜和脉络膜改变的理解，一组临床和遗传异质性疾病，可能因几种需要及时诊断的血管疾病而复杂化。在这次审查中,我们旨在全面总结OCT-A在IRD诊断和管理中的所有临床应用，突出视网膜色素变性的重要血管发现，Stargardt病,脉络膜炎,最佳疾病和其他不太常见的视网膜营养不良形式。还将讨论这种新颖成像模式的所有优点和局限性。
