Abstract：
Syringoma is a common but refractory benign skin tumor. Conventional treatment, such as ultra-pulsed carbon dioxide (CO2 ) laser or cryotherapy, often requires multiple treatment and can easily cause prolonged erythema, scarring, or depression, which are frustrating, so there is an urgent need to seek a safer and more effective method. In this article, we tried to demonstrate the Er:YAG laser combined with botulinum toxin A (BTXA) as a safer and more efficacious method for treating syringomas.
METHODS: Twenty-one patients with local syringomas were treated with erbium laser ablation. Immediately after laser treatment, approximately 10 units of BTXA were sprayed on the wound for 10 min.
RESULTS: In total, 21 patients underwent 1.62 ± 0.74 treatments; their Periorbital Syringoma Severity Index (PSSI) score declined from 4.19 (before treatment) to 1.10 (after treatment), and the number of treatments was significantly lower than those reported in previous literature using the erbium laser alone.
CONCLUSIONS: The Er:YAG laser combined with botulinum toxin A for the treatment of syringoma is a safer and more effective treatment than traditional treatment methods.
METHODS: Twenty-one patients with local syringomas were treated with erbium laser ablation. Immediately after laser treatment, approximately 10 units of BTXA were sprayed on the wound for 10 min.
RESULTS: In total, 21 patients underwent 1.62 ± 0.74 treatments; their Periorbital Syringoma Severity Index (PSSI) score declined from 4.19 (before treatment) to 1.10 (after treatment), and the number of treatments was significantly lower than those reported in previous literature using the erbium laser alone.
CONCLUSIONS: The Er:YAG laser combined with botulinum toxin A for the treatment of syringoma is a safer and more effective treatment than traditional treatment methods.
摘要：
汗管瘤是一种常见但难治的良性皮肤肿瘤。常规治疗,例如超脉冲二氧化碳（CO2）激光或冷冻疗法，通常需要多次治疗，很容易导致长时间的红斑，疤痕,或抑郁症，令人沮丧的是，因此，迫切需要寻求一种更安全、更有效的方法。在这篇文章中,我们试图证明Er:YAG激光联合肉毒杆菌毒素A（BTXA）是一种更安全、更有效的治疗汗管瘤的方法。
方法：对21例局部汗管瘤患者进行铒激光消融治疗。激光治疗后立即，将约10单位的BTXA喷洒在伤口上10分钟。
结果：总计，21例患者接受了1.62±0.74治疗；他们的眶周液管瘤严重程度指数（PSSI）评分从4.19（治疗前）下降到1.10（治疗后），治疗次数明显低于以往文献报道的单独使用铒激光的治疗次数。
结论：Er:YAG激光联合A型肉毒毒素治疗汗管瘤比传统治疗方法更安全、有效。
方法：对21例局部汗管瘤患者进行铒激光消融治疗。激光治疗后立即，将约10单位的BTXA喷洒在伤口上10分钟。
结果：总计，21例患者接受了1.62±0.74治疗；他们的眶周液管瘤严重程度指数（PSSI）评分从4.19（治疗前）下降到1.10（治疗后），治疗次数明显低于以往文献报道的单独使用铒激光的治疗次数。
结论：Er:YAG激光联合A型肉毒毒素治疗汗管瘤比传统治疗方法更安全、有效。
