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Abstract：
Blenderized tube feeds (blends) are associated with lower hospital admissions and reduced gastroesophageal symptoms, but their high viscosity may theoretically prolong gastric emptying. Our objective was to compare differences in gastric emptying with blends vs with formula.
We retrospectively identified individuals 6 months to 20 years with enteral tubes who underwent 1-h liquid gastric emptying scintigraphy from 1998 to 2020 at Boston Children\'s Hospital. Examinations were excluded if a postpyloric tube was present, tracer was administered orally or with diet differing from habitual, habitual diet was indeterminable, imaging was terminated early, or >50% of input counts emptied during bolus administration. Emptying was classified as delayed if gastric residual at 1 h was ≥60% of ingested dose.
Eighteen examinations (15 individuals) were performed with blends and 35 examinations (32 individuals) with formula. Although percentage of residual at 1 h was significantly higher in patients receiving blends compared with formula (54 ± 17 vs 40 ± 25, P = 0.04), the number of patients with delayed gastric emptying did not differ (39% vs 29%, respectively, P = 0.54). Type of diet, feed volume or concurrent medications did not predict delayed gastric emptying. Children with blends received higher bolus volumes (106 ± 55 vs 66 ± 59 ml; P = 0.02), and this significantly predicted percentage of residual (β = 0.14; P = 0.01).
The proportion of patients with delayed gastric emptying was similar in children receiving blends and formula. Although the mean percentage of gastric residual was higher with blends, this may be explained by higher bolus volumes administered. This preliminary work suggests that blends compare favorably to formula.
We retrospectively identified individuals 6 months to 20 years with enteral tubes who underwent 1-h liquid gastric emptying scintigraphy from 1998 to 2020 at Boston Children\'s Hospital. Examinations were excluded if a postpyloric tube was present, tracer was administered orally or with diet differing from habitual, habitual diet was indeterminable, imaging was terminated early, or >50% of input counts emptied during bolus administration. Emptying was classified as delayed if gastric residual at 1 h was ≥60% of ingested dose.
Eighteen examinations (15 individuals) were performed with blends and 35 examinations (32 individuals) with formula. Although percentage of residual at 1 h was significantly higher in patients receiving blends compared with formula (54 ± 17 vs 40 ± 25, P = 0.04), the number of patients with delayed gastric emptying did not differ (39% vs 29%, respectively, P = 0.54). Type of diet, feed volume or concurrent medications did not predict delayed gastric emptying. Children with blends received higher bolus volumes (106 ± 55 vs 66 ± 59 ml; P = 0.02), and this significantly predicted percentage of residual (β = 0.14; P = 0.01).
The proportion of patients with delayed gastric emptying was similar in children receiving blends and formula. Although the mean percentage of gastric residual was higher with blends, this may be explained by higher bolus volumes administered. This preliminary work suggests that blends compare favorably to formula.
摘要：
背景：混合管饲料（混合物）与住院人数减少和胃食管症状减少有关，但它们的高粘度理论上可能会延长胃排空。我们的目的是比较混合物与配方在胃排空方面的差异。
方法：我们回顾性地确定了1998-2020年在波士顿儿童医院接受1小时液体胃排空闪烁显像的6个月至20岁的肠内导管患者。如果幽门后管就位，则排除检查，示踪剂口服给药或与习惯性饮食不同，习惯性饮食是不确定的，成像提前终止,或>50%的输入计数在喂养期间清空。如果1h时的胃残留≥摄入剂量的60％，则将排空分类为延迟。
结果：用混合物进行了18次检查（15人），用配方进行了35次检查（32人）。尽管接受混合物的患者在1h时的残留百分比显着高于配方（54±17vs.40±25，P=0.04），胃排空延迟的患者人数没有差异(39%与分别为29%，P=0.54）。饮食类型,饲料量或同时用药并不能预测胃排空延迟.混合的儿童接受了更高的推注量（106±55mL与66±59mL,P=0.02),这显著预测了%残差(β=0.14，P=0.01)。
结论：在接受混合物和配方食品的儿童中，胃排空延迟的患者比例相似。尽管混合物的平均胃残留百分比较高，这可以解释为更高的推注量给药.这项初步工作表明，共混物与配方配方相比具有优势。本文受版权保护。保留所有权利。
方法：我们回顾性地确定了1998-2020年在波士顿儿童医院接受1小时液体胃排空闪烁显像的6个月至20岁的肠内导管患者。如果幽门后管就位，则排除检查，示踪剂口服给药或与习惯性饮食不同，习惯性饮食是不确定的，成像提前终止,或>50%的输入计数在喂养期间清空。如果1h时的胃残留≥摄入剂量的60％，则将排空分类为延迟。
结果：用混合物进行了18次检查（15人），用配方进行了35次检查（32人）。尽管接受混合物的患者在1h时的残留百分比显着高于配方（54±17vs.40±25，P=0.04），胃排空延迟的患者人数没有差异(39%与分别为29%，P=0.54）。饮食类型,饲料量或同时用药并不能预测胃排空延迟.混合的儿童接受了更高的推注量（106±55mL与66±59mL,P=0.02),这显著预测了%残差(β=0.14，P=0.01)。
结论：在接受混合物和配方食品的儿童中，胃排空延迟的患者比例相似。尽管混合物的平均胃残留百分比较高，这可以解释为更高的推注量给药.这项初步工作表明，共混物与配方配方相比具有优势。本文受版权保护。保留所有权利。
