Abstract：
OBJECTIVE: The aim of this study is to analyze the distribution of visual field (VF) mean defect (MD) in six subgroups of glaucoma patients at baseline and follow-up.
METHODS: We assessed glaucoma patients treated in a Spanish tertiary care setting with a follow-up of at least 10 months. We have included 1036 visual fields and the following glaucoma subtypes: open-Angle Glaucoma (OAG); Angle-Closure Glaucoma (ACG); Congenital Glaucoma (CG); Ocular hypertension (OHT); Pseudoexfoliative Glaucoma (PSXG); Pigmentary Glaucoma (PG). We have calculated the baseline MD and the progression MD. We have stratified the MD progression in slow (MD rate > -0.5 dB/year); moderate (MD rate between -0.5 and -1 dB/year) fast (MD rate between -1 and -2 dB/year) and catastrophic (<-2 dB/year) progression and their glaucoma subtype.
RESULTS: The glaucoma types with the worse baseline MD were CG and PG. We found significant differences after comparing the baseline MD of CG and OAG, ACG, OHT and between PG and OHT. Concerning the MD progression rate: OAG 73.54% showed slow MD progression rate; 9.85% fast; 7.3% moderate and 9.3% catastrophic. ACG 82.22% slow; 8.89% moderate; 2.22% fast and 6.67% catastrophic. CG 68.83% slow; 9.09% fast; 7.79% moderate and 14.29% catastrophic. OHT 88.6% slow; 6.14% moderate; 4.39% fast and 0.88% catastrophic. PSXG 63.24% slow, 13.24% moderate; 8.8% fast and 14.7% catastrophic. PG 89.29% slow; 3.57% moderate and 7.1% fast.
CONCLUSIONS: The CG requires special attention because of its aggressive presentation and progression.
METHODS: We assessed glaucoma patients treated in a Spanish tertiary care setting with a follow-up of at least 10 months. We have included 1036 visual fields and the following glaucoma subtypes: open-Angle Glaucoma (OAG); Angle-Closure Glaucoma (ACG); Congenital Glaucoma (CG); Ocular hypertension (OHT); Pseudoexfoliative Glaucoma (PSXG); Pigmentary Glaucoma (PG). We have calculated the baseline MD and the progression MD. We have stratified the MD progression in slow (MD rate > -0.5 dB/year); moderate (MD rate between -0.5 and -1 dB/year) fast (MD rate between -1 and -2 dB/year) and catastrophic (<-2 dB/year) progression and their glaucoma subtype.
RESULTS: The glaucoma types with the worse baseline MD were CG and PG. We found significant differences after comparing the baseline MD of CG and OAG, ACG, OHT and between PG and OHT. Concerning the MD progression rate: OAG 73.54% showed slow MD progression rate; 9.85% fast; 7.3% moderate and 9.3% catastrophic. ACG 82.22% slow; 8.89% moderate; 2.22% fast and 6.67% catastrophic. CG 68.83% slow; 9.09% fast; 7.79% moderate and 14.29% catastrophic. OHT 88.6% slow; 6.14% moderate; 4.39% fast and 0.88% catastrophic. PSXG 63.24% slow, 13.24% moderate; 8.8% fast and 14.7% catastrophic. PG 89.29% slow; 3.57% moderate and 7.1% fast.
CONCLUSIONS: The CG requires special attention because of its aggressive presentation and progression.
摘要：
目的：这项研究的目的是分析基线和随访时六个青光眼患者亚组的视野（VF）平均缺损（MD）的分布。
方法：我们评估了在西班牙三级护理环境中治疗的青光眼患者，随访至少10个月。我们已经纳入了1036个视野和以下青光眼亚型：开角型青光眼（OAG）;闭角型青光眼（ACG）;先天性青光眼（CG）;高眼压（OHT）;假性剥脱性青光眼（PSXG）;色素性青光眼（PG）。我们已经计算了基线MD和进展MD。我们已将MD进展分为缓慢（MD率>-0.5dB/年）；中度（MD率在-0.5和-1dB/年之间）快速（MD率在-1和-2dB/年之间）和灾难性（<-2dB/年）进展及其青光眼亚型。
结果：基线MD较差的青光眼类型为CG和PG。在比较CG和OAG的基线MD后，我们发现显著差异，ACG,OHT和PG和OHT之间。关于MD进展率：OAG73.54％显示MD进展率慢；9.85％快；7.3％中度和9.3％灾难性。ACG慢82.22%；中度8.89%；快2.22%，灾难性6.67%。CG慢68.83%；快9.09%；中度7.79%，灾难性14.29%。OHT慢88.6%；中度6.14%；快速4.39%，灾难性0.88%。PSXG慢63.24%,13.24%适度；8.8%快速，14.7%灾难性。PG89.29%缓慢；3.57%中等，7.1%快。
结论：CG由于其积极的表现和进展而需要特别注意。
方法：我们评估了在西班牙三级护理环境中治疗的青光眼患者，随访至少10个月。我们已经纳入了1036个视野和以下青光眼亚型：开角型青光眼（OAG）;闭角型青光眼（ACG）;先天性青光眼（CG）;高眼压（OHT）;假性剥脱性青光眼（PSXG）;色素性青光眼（PG）。我们已经计算了基线MD和进展MD。我们已将MD进展分为缓慢（MD率>-0.5dB/年）；中度（MD率在-0.5和-1dB/年之间）快速（MD率在-1和-2dB/年之间）和灾难性（<-2dB/年）进展及其青光眼亚型。
结果：基线MD较差的青光眼类型为CG和PG。在比较CG和OAG的基线MD后，我们发现显著差异，ACG,OHT和PG和OHT之间。关于MD进展率：OAG73.54％显示MD进展率慢；9.85％快；7.3％中度和9.3％灾难性。ACG慢82.22%；中度8.89%；快2.22%，灾难性6.67%。CG慢68.83%；快9.09%；中度7.79%，灾难性14.29%。OHT慢88.6%；中度6.14%；快速4.39%，灾难性0.88%。PSXG慢63.24%,13.24%适度；8.8%快速，14.7%灾难性。PG89.29%缓慢；3.57%中等，7.1%快。
结论：CG由于其积极的表现和进展而需要特别注意。
