PDF(Pubmed)
Abstract：
UNASSIGNED: The co-presentation of severe obesity (SO) and global developmental delay (GDD) in Canadian preschool children has not been examined. However, SO and GDD may require syndromic diagnoses and unique management considerations.
UNASSIGNED: To determine (1) minimum incidence; (2) age of onset and risk factors; and (3) health care utilization for co-presenting SO and GDD.
UNASSIGNED: Through the Canadian Paediatric Surveillance Program (CPSP), a monthly form was distributed to participants from February 2018 to January 2020 asking for reports of new cases of SO and GDD among children ≤5 years of age. We performed descriptive statistics for quantitative questions and qualitative content analysis for open-ended questions.
UNASSIGNED: Forty-seven cases (64% male; 51% white; mean age: 3.5 ± 1.2 years) were included. Age of first weight concern was 2.5 ± 1.3 years and age of GDD diagnosis was 2.7 ± 1.4 years. Minimum incidence of SO and GDD was 3.3 cases per 100,000 for ≤5 years of age per year. Identified problems included school and/or behavioural problems (n = 17; 36%), snoring (n = 14; 30%), and asthma/recurrent wheeze (n = 10; 21%). Mothers of 32% of cases (n = 15) had obesity and 21% of cases (n = 10) received neonatal intensive care. Microarray was ordered for 57% (n = 27) of children. A variety of clinicians and services were accessed. As reported by CPSP participants, challenges faced by families and health service access were barriers to care.
UNASSIGNED: Children with SO and GDD have multiple comorbidities, and require early identification and referral to appropriate services. These cases may also benefit from additional testing to rule out known genetic obesity syndromes.
UNASSIGNED: To determine (1) minimum incidence; (2) age of onset and risk factors; and (3) health care utilization for co-presenting SO and GDD.
UNASSIGNED: Through the Canadian Paediatric Surveillance Program (CPSP), a monthly form was distributed to participants from February 2018 to January 2020 asking for reports of new cases of SO and GDD among children ≤5 years of age. We performed descriptive statistics for quantitative questions and qualitative content analysis for open-ended questions.
UNASSIGNED: Forty-seven cases (64% male; 51% white; mean age: 3.5 ± 1.2 years) were included. Age of first weight concern was 2.5 ± 1.3 years and age of GDD diagnosis was 2.7 ± 1.4 years. Minimum incidence of SO and GDD was 3.3 cases per 100,000 for ≤5 years of age per year. Identified problems included school and/or behavioural problems (n = 17; 36%), snoring (n = 14; 30%), and asthma/recurrent wheeze (n = 10; 21%). Mothers of 32% of cases (n = 15) had obesity and 21% of cases (n = 10) received neonatal intensive care. Microarray was ordered for 57% (n = 27) of children. A variety of clinicians and services were accessed. As reported by CPSP participants, challenges faced by families and health service access were barriers to care.
UNASSIGNED: Children with SO and GDD have multiple comorbidities, and require early identification and referral to appropriate services. These cases may also benefit from additional testing to rule out known genetic obesity syndromes.
摘要：
■尚未检查加拿大学龄前儿童中严重肥胖（SO）和全球发育迟缓（GDD）的共同表现。然而,SO和GDD可能需要综合征诊断和独特的管理考虑。
■确定（1）最低发病率；（2）发病年龄和危险因素；（3）共同提供SO和GDD的医疗保健利用。
■通过加拿大儿科监测计划（CPSP），从2018年2月至2020年1月,我们向参与者分发了每月表格,询问≤5岁儿童中SO和GDD新病例的报告.我们对定量问题进行了描述性统计，对开放式问题进行了定性内容分析。
■包括47例（男性64％；白人51％；平均年龄：3.5±1.2岁）。首次关注体重的年龄为2.5±1.3岁，GDD诊断的年龄为2.7±1.4岁。每年≤5岁时，SO和GDD的最低发生率为每100,000例中3.3例。确定的问题包括学校和/或行为问题（n=17；36％），打鼾（n=14；30%），哮喘/反复喘息（n=10；21%）。32％的病例（n=15）的母亲患有肥胖症，21％的病例（n=10）接受了新生儿重症监护。57％（n=27）的儿童订购了微阵列。获得了各种临床医生和服务。正如CPSP参与者报告的那样，家庭面临的挑战和医疗服务的获取是护理的障碍。
■患有SO和GDD的儿童有多种合并症，并要求及早识别和转介适当的服务。这些病例也可能受益于额外的测试，以排除已知的遗传性肥胖综合征。
■确定（1）最低发病率；（2）发病年龄和危险因素；（3）共同提供SO和GDD的医疗保健利用。
■通过加拿大儿科监测计划（CPSP），从2018年2月至2020年1月,我们向参与者分发了每月表格,询问≤5岁儿童中SO和GDD新病例的报告.我们对定量问题进行了描述性统计，对开放式问题进行了定性内容分析。
■包括47例（男性64％；白人51％；平均年龄：3.5±1.2岁）。首次关注体重的年龄为2.5±1.3岁，GDD诊断的年龄为2.7±1.4岁。每年≤5岁时，SO和GDD的最低发生率为每100,000例中3.3例。确定的问题包括学校和/或行为问题（n=17；36％），打鼾（n=14；30%），哮喘/反复喘息（n=10；21%）。32％的病例（n=15）的母亲患有肥胖症，21％的病例（n=10）接受了新生儿重症监护。57％（n=27）的儿童订购了微阵列。获得了各种临床医生和服务。正如CPSP参与者报告的那样，家庭面临的挑战和医疗服务的获取是护理的障碍。
■患有SO和GDD的儿童有多种合并症，并要求及早识别和转介适当的服务。这些病例也可能受益于额外的测试，以排除已知的遗传性肥胖综合征。
