PDF(Pubmed)
Abstract：
UNASSIGNED: Syphilis is a treatable bacterial infection caused by Treponema pallidum. There has been a change in incidence of syphilis in various nations over the years.
UNASSIGNED: To study the epidemiological trends, demographic profile, high-risk behaviour, clinical pattern, and stage of syphilis over the last ten years in patients presenting to an STD clinic in a tertiary care hospital.
UNASSIGNED: This was a retrospective observational study over ten years. Records of all confirmed syphilis cases were analysed in relation to demography and clinical profile.
UNASSIGNED: There were a total of 3,110 STD patients among whom 31 cases (accounting for 0.99%) of confirmed syphilis were seen. There was a significant increase in cases in the last five years of study, especially in the last year. An increase in primary (PS) and secondary syphilis (SS) was observed. Males outnumbered females (3:1). Mean age of patients was 35.0 ± 11.53 years. Professionals were most common (22.6%) having syphilis followed by farmers (19.35%). A significant proportion (45.1%) of our patients were at least graduates. Unprotected sex was seen in all the patients followed by extramarital/premarital sex (71.35%). There were 16.12% of cases who had a history of paid sex and 9.7% were homosexuals. SS and latent syphilis were more common (38.7% each) than PS (19.35%). In PS single chancre and in SS truncal asymptomatic rash was the commonest clinical presentation. Limitation: Single-centre study, including only self-reported patients leading to a small sample size, is the major limitation of the study.
UNASSIGNED: The increased trend of primary and secondary syphilis in recent years highlights that there is a risk of an impending epidemic.
UNASSIGNED: To study the epidemiological trends, demographic profile, high-risk behaviour, clinical pattern, and stage of syphilis over the last ten years in patients presenting to an STD clinic in a tertiary care hospital.
UNASSIGNED: This was a retrospective observational study over ten years. Records of all confirmed syphilis cases were analysed in relation to demography and clinical profile.
UNASSIGNED: There were a total of 3,110 STD patients among whom 31 cases (accounting for 0.99%) of confirmed syphilis were seen. There was a significant increase in cases in the last five years of study, especially in the last year. An increase in primary (PS) and secondary syphilis (SS) was observed. Males outnumbered females (3:1). Mean age of patients was 35.0 ± 11.53 years. Professionals were most common (22.6%) having syphilis followed by farmers (19.35%). A significant proportion (45.1%) of our patients were at least graduates. Unprotected sex was seen in all the patients followed by extramarital/premarital sex (71.35%). There were 16.12% of cases who had a history of paid sex and 9.7% were homosexuals. SS and latent syphilis were more common (38.7% each) than PS (19.35%). In PS single chancre and in SS truncal asymptomatic rash was the commonest clinical presentation. Limitation: Single-centre study, including only self-reported patients leading to a small sample size, is the major limitation of the study.
UNASSIGNED: The increased trend of primary and secondary syphilis in recent years highlights that there is a risk of an impending epidemic.
摘要：
■梅毒是由梅毒螺旋体引起的可治疗的细菌感染。多年来，各个国家的梅毒发病率发生了变化。
■为了研究流行病学趋势，人口统计概况,高风险行为,临床模式，以及过去十年来到三级医院性病诊所就诊的患者的梅毒阶段。
■这是一项为期10年的回顾性观察研究。对所有确诊梅毒病例的记录进行了人口统计和临床分析。
■共有3,110名性病患者，其中31例（占0.99%）确诊梅毒。在过去五年的研究中，病例显着增加，尤其是去年。观察到原发性（PS）和继发性梅毒（SS）的增加。雄性数量超过雌性（3:1）。患者平均年龄为35.0±11.53岁。专业人员最常见（22.6％）患有梅毒，其次是农民（19.35％）。我们的患者中有很大一部分（45.1％）至少是毕业生。所有患者均出现无保护性行为，其次是婚外/婚前性行为（71.35％）。有有偿性行为史的病例占16.12％，同性恋者占9.7％。SS和潜伏梅毒比PS（19.35％）更常见（各38.7％）。在PS单下和SS中，无症状的躯干皮疹是最常见的临床表现。局限性：单中心研究，仅包括自我报告的患者，导致样本量小，是这项研究的主要局限性。
■近年来，原发性和继发性梅毒的增加趋势凸显了即将流行的风险。
■为了研究流行病学趋势，人口统计概况,高风险行为,临床模式，以及过去十年来到三级医院性病诊所就诊的患者的梅毒阶段。
■这是一项为期10年的回顾性观察研究。对所有确诊梅毒病例的记录进行了人口统计和临床分析。
■共有3,110名性病患者，其中31例（占0.99%）确诊梅毒。在过去五年的研究中，病例显着增加，尤其是去年。观察到原发性（PS）和继发性梅毒（SS）的增加。雄性数量超过雌性（3:1）。患者平均年龄为35.0±11.53岁。专业人员最常见（22.6％）患有梅毒，其次是农民（19.35％）。我们的患者中有很大一部分（45.1％）至少是毕业生。所有患者均出现无保护性行为，其次是婚外/婚前性行为（71.35％）。有有偿性行为史的病例占16.12％，同性恋者占9.7％。SS和潜伏梅毒比PS（19.35％）更常见（各38.7％）。在PS单下和SS中，无症状的躯干皮疹是最常见的临床表现。局限性：单中心研究，仅包括自我报告的患者，导致样本量小，是这项研究的主要局限性。
■近年来，原发性和继发性梅毒的增加趋势凸显了即将流行的风险。
