PDF(Pubmed)
Abstract：
BACKGROUND: Escherichia fergusonii is a common conditionally pathogenic bacterium that infects humans and animals. E. fergusonii has been reported to cause diarrhea, respiratory disease, and septicemia, but it is rarely reported to cause skin infections in animals. E. fergusonii has been isolated from the skin and muscular tissue of Chinese pangolin (Manis pentadactyla aurita). To date, there have been no reports of Chinese pangolins with clinical signs of skin diseases.
METHODS: This case report describes the clinical case of a subadult (bodyweight: 1.1 kg) female Chinese pangolin from wild rescue with pustules and subcutaneous suppurative infection due to E. fergusonii in the abdominal skin. Bacterial culture, Biochemical analysis, PCR and histopathology were utilized to identify the bacteria in the pustule puncture fluid and infected tissue. To the best of our knowledge, this is the first report of E. fergusonii-related pustules on a Chinese pangolin.
CONCLUSIONS: This case report presents the first observed skin infection in a Chinese pangolin. E. fergusonii infection should be considered as a possible differential diagnosis of pustules and subcutaneous suppurative skin conditions in Chinese pangolins, and we also provide several recommendations for the diagnosis and treatment of this disease.
METHODS: This case report describes the clinical case of a subadult (bodyweight: 1.1 kg) female Chinese pangolin from wild rescue with pustules and subcutaneous suppurative infection due to E. fergusonii in the abdominal skin. Bacterial culture, Biochemical analysis, PCR and histopathology were utilized to identify the bacteria in the pustule puncture fluid and infected tissue. To the best of our knowledge, this is the first report of E. fergusonii-related pustules on a Chinese pangolin.
CONCLUSIONS: This case report presents the first observed skin infection in a Chinese pangolin. E. fergusonii infection should be considered as a possible differential diagnosis of pustules and subcutaneous suppurative skin conditions in Chinese pangolins, and we also provide several recommendations for the diagnosis and treatment of this disease.
摘要：
背景：费氏大肠杆菌是一种常见的条件致病性细菌，可感染人类和动物。据报道，E.Fergusonii会引起腹泻，呼吸道疾病,和败血症,但很少有报道会引起动物皮肤感染。已从中国穿山甲（Manispentadactylaaurita）的皮肤和肌肉组织中分离出E.fergusonii。迄今为止,没有中国穿山甲有皮肤病临床症状的报道。
方法：本病例报告描述了1例亚成年（体重：1.1kg）雌性中国穿山甲的临床病例，该穿山甲因腹部皮肤中的E.Fergusonii引起脓疱和皮下化脓性感染。细菌培养,生化分析,利用PCR和组织病理学来鉴定脓疱穿刺液和感染组织中的细菌。据我们所知,这是中国穿山甲上与E.Fergusonii相关的脓疱的首次报道。
结论：本病例报告显示了首次观察到的中国穿山甲皮肤感染。应将E.Fergusonii感染视为中国穿山甲中脓疱和皮下化脓性皮肤疾病的可能鉴别诊断，我们还为这种疾病的诊断和治疗提供了一些建议。
方法：本病例报告描述了1例亚成年（体重：1.1kg）雌性中国穿山甲的临床病例，该穿山甲因腹部皮肤中的E.Fergusonii引起脓疱和皮下化脓性感染。细菌培养,生化分析,利用PCR和组织病理学来鉴定脓疱穿刺液和感染组织中的细菌。据我们所知,这是中国穿山甲上与E.Fergusonii相关的脓疱的首次报道。
结论：本病例报告显示了首次观察到的中国穿山甲皮肤感染。应将E.Fergusonii感染视为中国穿山甲中脓疱和皮下化脓性皮肤疾病的可能鉴别诊断，我们还为这种疾病的诊断和治疗提供了一些建议。
