PDF(Pubmed)
Abstract：
Previous studies showed the adverse impacts of air pollution on headache attacks in developed countries. However, evidence is limited to the impact of exposure to air pollutants on headache attacks. In this study, we aimed to explore the impact of nitrogen dioxide (NO2) exposure on neurology clinic visits (NCVs) for headache onsets.
Records of NCVs for headaches, concentrations of ambient NO2, and meteorological variables were collected in Wuhan, China, from January 1st, 2017, to November 30th, 2019. A time-series study was conducted to investigate the short-term effects of NO2 exposure on daily NCVs for headaches. Stratified analyses were also computed according to season, age, and sex, and the exposure-response (E-R) curve was then plotted.
A total of 11,436 records of NCVs for headaches were enrolled in our study during the period. A 10-μg/m3 increase of ambient NO2 corresponded to a 3.64% elevation of daily NCVs for headaches (95%CI: 1.02%, 6.32%, P = 0.006). Moreover, females aged less than 50 years of age were more susceptible compared to males (4.10% vs. 2.97%, P = 0.007). The short-term effects of NO2 exposure on daily NCVs for headaches were stronger in cool seasons than in warm seasons (6.31% vs. 0.79%, P = 0.0009).
Our findings highlight that short-term exposure to ambient NO2 positively correlated with NCVs for headaches in Wuhan, China, and the adverse effects varied by season, age, and sex.
Records of NCVs for headaches, concentrations of ambient NO2, and meteorological variables were collected in Wuhan, China, from January 1st, 2017, to November 30th, 2019. A time-series study was conducted to investigate the short-term effects of NO2 exposure on daily NCVs for headaches. Stratified analyses were also computed according to season, age, and sex, and the exposure-response (E-R) curve was then plotted.
A total of 11,436 records of NCVs for headaches were enrolled in our study during the period. A 10-μg/m3 increase of ambient NO2 corresponded to a 3.64% elevation of daily NCVs for headaches (95%CI: 1.02%, 6.32%, P = 0.006). Moreover, females aged less than 50 years of age were more susceptible compared to males (4.10% vs. 2.97%, P = 0.007). The short-term effects of NO2 exposure on daily NCVs for headaches were stronger in cool seasons than in warm seasons (6.31% vs. 0.79%, P = 0.0009).
Our findings highlight that short-term exposure to ambient NO2 positively correlated with NCVs for headaches in Wuhan, China, and the adverse effects varied by season, age, and sex.
摘要：
背景：先前的研究表明，在发达国家，空气污染对头痛发作的不利影响。然而,证据仅限于暴露于空气污染物对头痛发作的影响。在这项研究中,我们旨在探讨二氧化氮(NO2)暴露对神经内科就诊(NCV)头痛发作的影响.
方法：头痛的NCV记录，收集了武汉的环境NO2浓度和气象变量，中国,从1月1日,2017年11月30日,2019.进行了时间序列研究，以调查NO2暴露对头痛的每日NCV的短期影响。还根据季节计算了分层分析，年龄,和性,然后绘制暴露-反应(E-R)曲线。
结果：本研究期间共纳入了11,436条头痛的NCV记录。环境NO2的10-μg/m3增加对应于头痛的每日NCV的3.64％升高（95CI：1.02％，6.32%,P=0.006)。此外，与男性相比，年龄小于50岁的女性更容易受到影响(4.10%vs.2.97%,P=0.007)。在凉爽季节，NO2暴露对头痛的每日NCV的短期影响比在温暖季节更强（6.31％vs.0.79%，P=0.0009)。
结论：我们的发现强调，在武汉，短期暴露于环境NO2与NCV的头痛呈正相关，中国,不利影响因季节而异，年龄,和性爱。
方法：头痛的NCV记录，收集了武汉的环境NO2浓度和气象变量，中国,从1月1日,2017年11月30日,2019.进行了时间序列研究，以调查NO2暴露对头痛的每日NCV的短期影响。还根据季节计算了分层分析，年龄,和性,然后绘制暴露-反应(E-R)曲线。
结果：本研究期间共纳入了11,436条头痛的NCV记录。环境NO2的10-μg/m3增加对应于头痛的每日NCV的3.64％升高（95CI：1.02％，6.32%,P=0.006)。此外，与男性相比，年龄小于50岁的女性更容易受到影响(4.10%vs.2.97%,P=0.007)。在凉爽季节，NO2暴露对头痛的每日NCV的短期影响比在温暖季节更强（6.31％vs.0.79%，P=0.0009)。
结论：我们的发现强调，在武汉，短期暴露于环境NO2与NCV的头痛呈正相关，中国,不利影响因季节而异，年龄,和性爱。
