PDF(Pubmed)
Abstract：
Acute rheumatic fever (ARF) is an autoimmune response that may occur after a group A Streptococcus (GAS) infection. Subcutaneous nodules are considered a rare manifestation of acute rheumatic fever with an incidence of 0%-10%. We present a case study of a 13-year-old girl who presented to us with subcutaneous nodules and articular involvement described as a non-migratory polyarticular joint pain involving the small joints of the hands, wrist, elbows, knees, and ankles for three months with poor response to the non-steroidal anti-inflammatory drug (NSAID) Ibuprofen. Accompanied with the presence of carditis, the patient fulfilled three major and two minor criteria of the revised Jones criteria 2015. Therefore, a diagnosis of acute rheumatic fever was made. The child was asymptomatic on subsequent visits, and although the subcutaneous nodules subsided, she will continue to receive penicillin every month for five years. We describe the successful diagnosis and management of a patient with ARF.
摘要：
急性风湿热（ARF）是一种自身免疫反应，可能在A组链球菌（GAS）感染后发生。皮下结节被认为是急性风湿热的罕见表现，发病率为0％-10％。我们提供了一个13岁女孩的案例研究，该女孩向我们展示了皮下结节和关节受累，被描述为涉及手部小关节的非转移性多关节疼痛，手腕,肘部,膝盖,和脚踝三个月，对非甾体抗炎药（NSAID）布洛芬反应不佳。伴随着心脏炎的出现，患者符合2015年修订的Jones标准的3个主要标准和2个次要标准.因此,诊断为急性风湿热。孩子在随后的就诊中无症状,虽然皮下结节消退了,五年来，她将继续每月接受青霉素。我们描述了ARF患者的成功诊断和治疗。
