PDF(Pubmed)
Abstract：
Relapsing polychondritis (RP) is a rare autoimmune disease in which recurrent and progressive chondritis occurs throughout the body. We report a case of a 56-year-old female subject presented as intermittent fever and cough, who was found obvious luminal stenosis and intense 18F-fluorodeoxyglucose (FDG) uptake in her larynx and trachea via bronchoscopy and FDG positron emission tomography/computed tomography (PET/CT). The auricular cartilage biopsy demonstrated chondritis. At first she was diagnosed as RP and treated by glucocorticoid and methotrexate, leading to completely response. Fever and cough recurred after 18 months, and FDG PET/CT were performed again and targeted a newfound nasopharyngeal lesion, where the biopsy proved to be an extranodal natural killer (NK)/T-cell lymphoma, nasal type.
摘要：
复发性多软骨炎（RP）是一种罕见的自身免疫性疾病，在整个身体中发生复发性和进行性软骨炎。我们报告了一例56岁的女性受试者，表现为间歇性发烧和咳嗽，通过支气管镜检查和FDG正电子发射断层扫描/计算机断层扫描（PET/CT）发现她的喉和气管中明显的管腔狭窄和强烈的18F-脱氧葡萄糖（FDG）摄取。耳廓软骨活检显示软骨炎。起初她被诊断为RP，并接受糖皮质激素和甲氨蝶呤治疗，导致完全的反应。18个月后发烧和咳嗽复发，再次进行FDGPET/CT，并针对新发现的鼻咽病变，活检证明是结外自然杀伤（NK）/T细胞淋巴瘤，鼻型。
