PDF(Pubmed)
Abstract：
Psychopathic traits involve interpersonal manipulation, callous affect, erratic lifestyle, and antisocial behavior. Though adult psychopathic traits emerge from both genetic and environmental risk, no studies have examined etiologic associations between adult psychopathic traits and experiences of parenting in childhood, or the extent to which parenting practices may impact the heritability of adult psychopathic traits using a genetically-informed design.
In total, 1842 adult twins from the community reported their current psychopathic traits and experiences of negative parenting during childhood. We fit bivariate genetic models to the data, decomposing the variance within, and the covariance between, psychopathic traits and perceived negative parenting into their genetic and environmental components. We then fit a genotype × environment interaction model to evaluate whether negative parenting moderated the etiology of psychopathic traits.
Psychopathic traits were moderately heritable with substantial non-shared environmental influences. There were significant associations between perceived negative parenting and three of four psychopathy facets (interpersonal manipulation, erratic lifestyle, antisocial tendencies, but not callous affect). These associations were attributable to a common non-shared environmental pathway and not to overlapping genetic effects. Additionally, we found that primarily shared environmental influences were stronger on psychopathic traits for individuals with a history of greater negative parenting.
Utilizing a genetically-informed design, we found that both genetic and non-shared environmental factors contribute to the emergence of psychopathic traits. Moreover, perceptions of negative parenting emerged as a clear environmental influence on the development of interpersonal, lifestyle, and antisocial features of psychopathy.
In total, 1842 adult twins from the community reported their current psychopathic traits and experiences of negative parenting during childhood. We fit bivariate genetic models to the data, decomposing the variance within, and the covariance between, psychopathic traits and perceived negative parenting into their genetic and environmental components. We then fit a genotype × environment interaction model to evaluate whether negative parenting moderated the etiology of psychopathic traits.
Psychopathic traits were moderately heritable with substantial non-shared environmental influences. There were significant associations between perceived negative parenting and three of four psychopathy facets (interpersonal manipulation, erratic lifestyle, antisocial tendencies, but not callous affect). These associations were attributable to a common non-shared environmental pathway and not to overlapping genetic effects. Additionally, we found that primarily shared environmental influences were stronger on psychopathic traits for individuals with a history of greater negative parenting.
Utilizing a genetically-informed design, we found that both genetic and non-shared environmental factors contribute to the emergence of psychopathic traits. Moreover, perceptions of negative parenting emerged as a clear environmental influence on the development of interpersonal, lifestyle, and antisocial features of psychopathy.
摘要：
背景：精神病特征涉及人际操纵，无情的影响，不稳定的生活方式,和反社会行为。尽管成人的精神病特征来自遗传和环境风险，没有研究检查成人精神病特征和童年育儿经历之间的病因学关联，或者在多大程度上，育儿实践可能会影响使用基因知情设计的成人精神病特征的遗传性。
方法：总共，1842年，来自社区的成年双胞胎报告了他们目前的精神病特征和童年时期消极育儿的经历。我们将双变量遗传模型拟合到数据中，分解内部的方差，和之间的协方差，精神病特征和对其遗传和环境成分的负面养育。然后，我们拟合基因型×环境相互作用模型，以评估负父母是否调节了精神病特征的病因。
结果：精神病特征具有中等遗传性，并具有大量的非共有环境影响。感知的消极父母教养与四个精神病方面中的三个(人际操纵，不稳定的生活方式,反社会倾向,但不是无情的影响)。这些关联归因于共同的非共享环境途径，而不是重叠的遗传效应。此外,我们发现，对于有较多负面育儿史的个体，主要是共同的环境影响对精神病特征的影响更大。
结论：利用基因知情设计，我们发现,遗传因素和非共有环境因素都有助于精神病特征的出现.此外，负面育儿观念作为对人际关系发展的明显环境影响而出现，生活方式,和精神病的反社会特征。
方法：总共，1842年，来自社区的成年双胞胎报告了他们目前的精神病特征和童年时期消极育儿的经历。我们将双变量遗传模型拟合到数据中，分解内部的方差，和之间的协方差，精神病特征和对其遗传和环境成分的负面养育。然后，我们拟合基因型×环境相互作用模型，以评估负父母是否调节了精神病特征的病因。
结果：精神病特征具有中等遗传性，并具有大量的非共有环境影响。感知的消极父母教养与四个精神病方面中的三个(人际操纵，不稳定的生活方式,反社会倾向,但不是无情的影响)。这些关联归因于共同的非共享环境途径，而不是重叠的遗传效应。此外,我们发现，对于有较多负面育儿史的个体，主要是共同的环境影响对精神病特征的影响更大。
结论：利用基因知情设计，我们发现,遗传因素和非共有环境因素都有助于精神病特征的出现.此外，负面育儿观念作为对人际关系发展的明显环境影响而出现，生活方式,和精神病的反社会特征。
