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Abstract：
Introduction Otosclerosis is a common cause of conductive hearing loss in the adult population that is caused by fixation of the stapes footplate. Cochlear otosclerosis may also present with sensorineural or mixed hearing loss. Surgery is the definitive treatment of choice and, during the procedure, sealing of the oval window with autologous tissue graft around the stapes prosthesis has been routinely done to improve hearing outcome and to mitigate postoperative complications. Objective To evaluate the efficacy of two different types of autologous tissue (vein or fat) grafts as oval window sealing materials in stapedotomy in improving short-term hearing outcomes. Methods In our study, 70 patients with otosclerosis who underwent primary stapedotomy were included. They were divided into group 1 (vein graft) and group 2 (fat graft) based on the type of sealing material used. All patients were followed-up at the end of 3 months, undergoing an audiometric examination to assess the hearing outcome. Results A total of 80% ( n = 28) of the patients in group1 had an air-bone gap (ABG) closure < 10dB, and, in group 2, 85.7% had an ABG closure < 10 dB; this difference was found to be statistically insignificant. A total of 42.9% ( n = 15) of the patients in group 1 and of 31.4% ( n = 11) in group 2 had a significant improvement in bone conduction, while 14.3% ( n = 5) of the patients in group 1 and 17.1% ( n = 6) in group 2 had worsening of average bone conduction postoperatively, which was found to be statistically insignificant. Conclusion Both vein and fat grafts had comparable effects on hearing outcomes when used as sealing materials in stapedotomy.
摘要：
简介耳硬化症是成人人群中传导性听力损失的常见原因，这是由stapes脚板的固定引起的。耳蜗耳硬化也可表现为感音神经性或混合性听力损失。手术是决定性的治疗选择,在手术过程中,常规使用骨假体周围的自体组织移植物密封卵形窗，以改善听力结果并减轻术后并发症。目的评价两种不同类型的自体组织(静脉或脂肪)移植体作为卵形窗密封材料在stapedoperation中改善短期听力结果的疗效。方法在我们的研究中,包括70例接受原发性staped切开术的耳硬化症患者。根据所用密封材料的类型，将它们分为第1组（静脉移植物）和第2组（脂肪移植物）。所有患者均在3个月结束时随访。接受听力测量检查以评估听力结果。结果第1组患者中有80％（n=28）的气-骨间隙（ABG）闭合<10dB，and,在第2组中,85.7%的ABG闭合<10dB;发现这一差异在统计学上无统计学意义.第1组患者中42.9％（n=15）和第2组患者中31.4％（n=11）的骨传导明显改善，而第1组14.3%(n=5)和第2组17.1%(n=6)的患者术后平均骨导恶化，这在统计上是不显著的。结论静脉和脂肪移植在stapedsometion切开术中用作密封材料对听力结果的影响相当。
