关键词: Talc acute respiratory distress syndrome malignant pleural effusion

来  源:   DOI:10.1177/11795476231170196   PDF(Pubmed)

Abstract:
Management of malignant pleural effusion is a medical challenge, and several methods have been proposed to deal with it including thoracentesis, indwelling pleural catheter placement, and chemical or mechanical pleurodesis. Each method, however, has its advantages and disadvantages. Talc pleurodesis is generally recognized as the most effective and safest method for the induction of chemical pleurodesis. However, in rare cases, it can lead to acute respiratory distress syndrome (ARDS). In this article, we report the case of a patient with metastatic adenocarcinoma to the pleura who presents with shortness of breath and malignant pleural effusion, develops ARDS after pleurodesis with talc, and expires despite the partial improvement of lung involvement. The symptoms and causes of this rare side effect as well as the methods that can be used to deal with it are reviewed in this article.
摘要:
恶性胸腔积液的管理是一个医学挑战,并提出了几种方法来处理它,包括胸腔穿刺术,留置胸膜导管放置,和化学或机械胸膜固定术。每种方法,然而,有它的优点和缺点。滑石胸膜固定术通常被认为是诱导化学胸膜固定术的最有效和最安全的方法。然而,在极少数情况下,可导致急性呼吸窘迫综合征(ARDS)。在这篇文章中,我们报道了一例胸膜转移性腺癌患者,表现为呼吸急促和恶性胸腔积液,用滑石粉胸膜固定术后出现ARDS,尽管肺部受累有部分改善,但仍到期。本文综述了这种罕见副作用的症状和原因以及可以用来处理它的方法。
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