PDF(Pubmed)
Abstract：
UNASSIGNED: This systematic review aimed to analyze the characteristics of different diagnostic techniques for micrognathia, summarize the consistent diagnostic criteria of each technique, and provide a simple and convenient prenatal diagnosis strategy for micrognathia.
UNASSIGNED: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the search was undertaken in three international databases (PubMed, Scopus, and Web of Science). The three reviewers assessed all papers and extracted the following variables: author\'s name and year of publication, country, study design, number of participants, gestational age, equipment for prenatal examination, biometric parameters related to micrognathia, main results.
UNASSIGNED: A total of 25 articles included in the analysis. Nineteen articles described cross-sectional studies (76 percent), 4 (16 percent) were case-control studies, and 2 (8 percent) were cohort studies. Fifteen studies (60 percent) had a prospective design, 9 (36 percent) had a retrospective design, and one (4 percent) had both prospective and retrospective design. Thirty-two percent of the studies (n = 8) were performed in USA, and the remaining studies were performed in China (n = 4), Israel (n = 3), Netherlands (n = 3), UK (n = 1), France (n = 1), Italy (n = 1), Belgium(n = 1), Germany (n = 1), Spain (n = 1), and Austria (n = 1). The prenatal diagnosis of micrognathia can be performed as early as possible in the first trimester, while the second and third trimester of pregnancy were the main prenatal diagnosis period. The articles that were included in the qualitative synthesis describe 30 biometric parameters related to the mandible.
UNASSIGNED: Of the 30 biometric parameters related to the mandible, 15 can obtain the simple and convenient diagnostic criteria or warning value for micrognathia. Based on these diagnostic criteria or warning value, clinicians can quickly make a preliminary judgment on facial deformities, to carry out cytologic examination to further clarify the diagnosis of micrognathia.
UNASSIGNED: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the search was undertaken in three international databases (PubMed, Scopus, and Web of Science). The three reviewers assessed all papers and extracted the following variables: author\'s name and year of publication, country, study design, number of participants, gestational age, equipment for prenatal examination, biometric parameters related to micrognathia, main results.
UNASSIGNED: A total of 25 articles included in the analysis. Nineteen articles described cross-sectional studies (76 percent), 4 (16 percent) were case-control studies, and 2 (8 percent) were cohort studies. Fifteen studies (60 percent) had a prospective design, 9 (36 percent) had a retrospective design, and one (4 percent) had both prospective and retrospective design. Thirty-two percent of the studies (n = 8) were performed in USA, and the remaining studies were performed in China (n = 4), Israel (n = 3), Netherlands (n = 3), UK (n = 1), France (n = 1), Italy (n = 1), Belgium(n = 1), Germany (n = 1), Spain (n = 1), and Austria (n = 1). The prenatal diagnosis of micrognathia can be performed as early as possible in the first trimester, while the second and third trimester of pregnancy were the main prenatal diagnosis period. The articles that were included in the qualitative synthesis describe 30 biometric parameters related to the mandible.
UNASSIGNED: Of the 30 biometric parameters related to the mandible, 15 can obtain the simple and convenient diagnostic criteria or warning value for micrognathia. Based on these diagnostic criteria or warning value, clinicians can quickly make a preliminary judgment on facial deformities, to carry out cytologic examination to further clarify the diagnosis of micrognathia.
摘要：
■本系统综述旨在分析不同诊断技术对小颌畸形的特点，总结每种技术的一致诊断标准，为小颌畸形的产前诊断提供了一种简单方便的策略。
■根据系统评价和荟萃分析（PRISMA）指南的首选报告项目，搜索是在三个国际数据库中进行的(PubMed，Scopus,和WebofScience)。三位审稿人评估了所有论文，并提取了以下变量：作者的姓名和发表年份，国家,研究设计，参与人数,胎龄,产前检查设备，与微颌相关的生物参数，主要结果。
■分析中总共包含25篇文章。十九篇文章描述了横断面研究(76%)，4（16％）是病例对照研究，2项(8%)为队列研究.15项研究（60％）具有前瞻性设计，9（36％）进行了回顾性设计，一个(4%)有前瞻性和回顾性设计。32%的研究（n=8）在美国进行，其余研究在中国进行(n=4)，以色列（n=3），荷兰（n=3），英国（n=1），法国（n=1），意大利（n=1），比利时（n=1），德国（n=1），西班牙（n=1），奥地利（n=1）。小颌畸形的产前诊断可以在妊娠早期尽早进行，妊娠中期和中期是产前诊断的主要时期。定性综合中包含的文章描述了与下颌骨相关的30个生物特征参数。
■在与下颌骨相关的30个生物特征参数中，15可以获得简单方便的小颌畸形诊断标准或预警值。根据这些诊断标准或警告值，临床医生可以快速对面部畸形做出初步判断，进行细胞学检查以进一步明确小颌畸形的诊断。
■根据系统评价和荟萃分析（PRISMA）指南的首选报告项目，搜索是在三个国际数据库中进行的(PubMed，Scopus,和WebofScience)。三位审稿人评估了所有论文，并提取了以下变量：作者的姓名和发表年份，国家,研究设计，参与人数,胎龄,产前检查设备，与微颌相关的生物参数，主要结果。
■分析中总共包含25篇文章。十九篇文章描述了横断面研究(76%)，4（16％）是病例对照研究，2项(8%)为队列研究.15项研究（60％）具有前瞻性设计，9（36％）进行了回顾性设计，一个(4%)有前瞻性和回顾性设计。32%的研究（n=8）在美国进行，其余研究在中国进行(n=4)，以色列（n=3），荷兰（n=3），英国（n=1），法国（n=1），意大利（n=1），比利时（n=1），德国（n=1），西班牙（n=1），奥地利（n=1）。小颌畸形的产前诊断可以在妊娠早期尽早进行，妊娠中期和中期是产前诊断的主要时期。定性综合中包含的文章描述了与下颌骨相关的30个生物特征参数。
■在与下颌骨相关的30个生物特征参数中，15可以获得简单方便的小颌畸形诊断标准或预警值。根据这些诊断标准或警告值，临床医生可以快速对面部畸形做出初步判断，进行细胞学检查以进一步明确小颌畸形的诊断。
