PDF(Pubmed)
Abstract：
UNASSIGNED: Premature ejaculation (PE) is a nosologic entity with issues in its conceptualization and definition.
UNASSIGNED: To understand if the altered sexual response in men with PE is in the orgasm phase, as currently assumed, or the arousal phase with difficulties in modulating, regulating, or decreasing sexual arousal.
UNASSIGNED: Men were recruited who looked for help for PE and met the diagnostic criteria according to clinical standards. The participants completed a sociodemographic survey and the Premature Ejaculation Diagnostic Tool. They also performed a masturbation exercise with a maximum of 5 stops, with the intention of prolonging the arousal phase. The time of the exercise was measured from the beginning of genital masturbation to ejaculation.
UNASSIGNED: We calculated the total time of the exercise, the median time at each start, and the number of dropouts. We performed a pairwise comparison analysis between starts and made a survival curve representing the percentage of men who remained in the exercise.
UNASSIGNED: A total of 481 men with PE participated (mean ± SD; age, 29.25 ± 8.72 years). We found that the expected median survival time until ejaculation was 317.00 seconds (95% CI, 288.34-345.65). However, the average time during stimulation decreased as the exercise progressed, and statistically significant differences were observed in their pairwise comparison (P < .001). Also, the chances of ejaculation increased as the exercise progressed, with 62.16% of the participants ejaculating before the end of the exercise. The results indicated increasing sexual arousal, where stops in stimulation were progressively less effective at maintaining ejaculation times at starts.
UNASSIGNED: We showed that the arousal phase is altered in PE, not the orgasm phase, and this could finally have implications in the diagnosis and/or treatment of this condition.
UNASSIGNED: The analysis of the times at starts and stops in a masturbation exercise in men with PE, had been barely addressed before. In the future, it would be important to verify the effect of stops during sexual intercourse and to incorporate a control group of men without PE.
UNASSIGNED: We propose a new conceptualization and definition for PE: progressive arousal disorder is the inability to modulate, regulate, or decrease arousal during any sexual activity, even with brief stops during sexual stimulation, causing unwanted ejaculation.
UNASSIGNED: To understand if the altered sexual response in men with PE is in the orgasm phase, as currently assumed, or the arousal phase with difficulties in modulating, regulating, or decreasing sexual arousal.
UNASSIGNED: Men were recruited who looked for help for PE and met the diagnostic criteria according to clinical standards. The participants completed a sociodemographic survey and the Premature Ejaculation Diagnostic Tool. They also performed a masturbation exercise with a maximum of 5 stops, with the intention of prolonging the arousal phase. The time of the exercise was measured from the beginning of genital masturbation to ejaculation.
UNASSIGNED: We calculated the total time of the exercise, the median time at each start, and the number of dropouts. We performed a pairwise comparison analysis between starts and made a survival curve representing the percentage of men who remained in the exercise.
UNASSIGNED: A total of 481 men with PE participated (mean ± SD; age, 29.25 ± 8.72 years). We found that the expected median survival time until ejaculation was 317.00 seconds (95% CI, 288.34-345.65). However, the average time during stimulation decreased as the exercise progressed, and statistically significant differences were observed in their pairwise comparison (P < .001). Also, the chances of ejaculation increased as the exercise progressed, with 62.16% of the participants ejaculating before the end of the exercise. The results indicated increasing sexual arousal, where stops in stimulation were progressively less effective at maintaining ejaculation times at starts.
UNASSIGNED: We showed that the arousal phase is altered in PE, not the orgasm phase, and this could finally have implications in the diagnosis and/or treatment of this condition.
UNASSIGNED: The analysis of the times at starts and stops in a masturbation exercise in men with PE, had been barely addressed before. In the future, it would be important to verify the effect of stops during sexual intercourse and to incorporate a control group of men without PE.
UNASSIGNED: We propose a new conceptualization and definition for PE: progressive arousal disorder is the inability to modulate, regulate, or decrease arousal during any sexual activity, even with brief stops during sexual stimulation, causing unwanted ejaculation.
摘要：
■早泄（PE）是一种病态实体，其概念化和定义存在问题。
■为了了解PE男性的性反应是否处于性高潮阶段，正如目前所假设的，或者调节困难的觉醒阶段，调节,或者减少性唤起。
■招募了寻求PE帮助并符合临床标准诊断标准的男性。参与者完成了社会人口统计学调查和早泄诊断工具。他们还进行了最多5次手淫练习，目的是延长觉醒期。从生殖器手淫开始到射精，测量运动时间。
■我们计算了锻炼的总时间，每次开始的中位数时间，以及辍学的人数。我们在开始之间进行了成对比较分析，并绘制了代表仍在运动中的男性百分比的生存曲线。
■共有481名患有PE的男性参加（平均值±SD；年龄，29.25±8.72年）。我们发现，直到射精的预期中位生存时间为317.00秒（95％CI，288.34-345.65）。然而,刺激期间的平均时间随着运动的进行而减少，两组比较差异有统计学意义(P<.001)。此外，随着运动的进行，射精的机会增加，62.16%的参与者在运动结束前射精。结果表明性唤起增加，停止刺激在开始时维持射精时间的效果逐渐降低。
■我们发现PE的觉醒期有改变，不是高潮阶段,这最终可能对这种情况的诊断和/或治疗产生影响。
■对PE男性的手淫练习中开始和停止时间的分析，以前几乎没有提到过。在未来,重要的是要验证性交过程中停止的效果，并纳入没有PE的男性对照组。
■我们为PE提出了一个新的概念和定义：进行性唤醒障碍是无法调节，规范,或在任何性活动中减少唤醒，即使在性刺激期间短暂停止，导致不想要的射精.
■为了了解PE男性的性反应是否处于性高潮阶段，正如目前所假设的，或者调节困难的觉醒阶段，调节,或者减少性唤起。
■招募了寻求PE帮助并符合临床标准诊断标准的男性。参与者完成了社会人口统计学调查和早泄诊断工具。他们还进行了最多5次手淫练习，目的是延长觉醒期。从生殖器手淫开始到射精，测量运动时间。
■我们计算了锻炼的总时间，每次开始的中位数时间，以及辍学的人数。我们在开始之间进行了成对比较分析，并绘制了代表仍在运动中的男性百分比的生存曲线。
■共有481名患有PE的男性参加（平均值±SD；年龄，29.25±8.72年）。我们发现，直到射精的预期中位生存时间为317.00秒（95％CI，288.34-345.65）。然而,刺激期间的平均时间随着运动的进行而减少，两组比较差异有统计学意义(P<.001)。此外，随着运动的进行，射精的机会增加，62.16%的参与者在运动结束前射精。结果表明性唤起增加，停止刺激在开始时维持射精时间的效果逐渐降低。
■我们发现PE的觉醒期有改变，不是高潮阶段,这最终可能对这种情况的诊断和/或治疗产生影响。
■对PE男性的手淫练习中开始和停止时间的分析，以前几乎没有提到过。在未来,重要的是要验证性交过程中停止的效果，并纳入没有PE的男性对照组。
■我们为PE提出了一个新的概念和定义：进行性唤醒障碍是无法调节，规范,或在任何性活动中减少唤醒，即使在性刺激期间短暂停止，导致不想要的射精.
