PDF(Pubmed)
Abstract：
BACKGROUND: Gastroesophageal reflux disease (GERD) is a condition caused by the reflux of stomach contents into the esophagus. Heartburn, chest discomfort, and regurgitation are the main symptoms. Medications, surgical procedures, and lifestyle modification are considered treatment options. Fasting is believed to be one of the lifestyle modifications that helps minimize GERD symptoms. Muslims abstain from eating, drinking, and smoking from dawn until dusk. The objectives of our study were to investigate the relationship between fasting and GERD symptoms and evaluate how fasting affects GERD symptoms in Saudi Arabia.
METHODS: This was a longitudinal study that selected GERD patients for its consecutive sampling. The patients answered the questionnaires at two separate times: once during Ramadan and once after Ramadan. A validated gastroesophageal reflux disease health-related quality of life (GERD-HRQL) self-administered survey was used.
RESULTS: After Ramadan, heartburn symptoms significantly decreased, particularly when lying down. Overall, the 45-point heartburn score decreased from 17.9 during Ramadan to 14.3 thereafter. The regurgitation score decreased from 12.3 during Ramadan to 9.9 after fasting, with statistical significance (P = .049). Although satisfaction was much higher after Ramadan (17% vs. 15.1%), there was no statistical significance (P = .422), and 45.3% of the patients were satisfied with their health state during Ramadan compared to 34% after Ramadan. There was no relationship between the severity of GERD symptoms before or after fasting and the type of food, the timing of eating, or the amount of food consumed.
CONCLUSIONS: The results suggested that Ramadan fasting may improve GERD symptoms. However, more studies are required to validate these results and comprehend the underlying mechanisms.
METHODS: This was a longitudinal study that selected GERD patients for its consecutive sampling. The patients answered the questionnaires at two separate times: once during Ramadan and once after Ramadan. A validated gastroesophageal reflux disease health-related quality of life (GERD-HRQL) self-administered survey was used.
RESULTS: After Ramadan, heartburn symptoms significantly decreased, particularly when lying down. Overall, the 45-point heartburn score decreased from 17.9 during Ramadan to 14.3 thereafter. The regurgitation score decreased from 12.3 during Ramadan to 9.9 after fasting, with statistical significance (P = .049). Although satisfaction was much higher after Ramadan (17% vs. 15.1%), there was no statistical significance (P = .422), and 45.3% of the patients were satisfied with their health state during Ramadan compared to 34% after Ramadan. There was no relationship between the severity of GERD symptoms before or after fasting and the type of food, the timing of eating, or the amount of food consumed.
CONCLUSIONS: The results suggested that Ramadan fasting may improve GERD symptoms. However, more studies are required to validate these results and comprehend the underlying mechanisms.
摘要：
背景：胃食管反流病（GERD）是由胃内容物回流到食道引起的疾病。胃灼热,胸部不适，反流是主要症状。药物,外科手术,和生活方式的改变被认为是治疗选择。禁食被认为是生活方式的改变之一，有助于减少GERD症状。穆斯林放弃进食，饮酒,从黎明到黄昏抽烟.我们研究的目的是调查禁食与GERD症状之间的关系，并评估禁食如何影响沙特阿拉伯的GERD症状。
方法：这是一项纵向研究，选择GERD患者进行连续采样。患者在两个不同的时间回答问卷：一次在斋月期间，一次在斋月之后。使用经过验证的胃食管反流病健康相关生活质量（GERD-HRQL）自我管理调查。
结果：斋月后，胃灼热症状明显减轻，尤其是躺下的时候。总的来说,45分的胃灼热评分从斋月期间的17.9降至之后的14.3分.反流评分从斋月期间的12.3下降到禁食后的9.9，具有统计学意义(P=0.049)。尽管斋月后满意度要高得多（17%vs.15.1%），差异无统计学意义(P=0.422),斋月期间，45.3％的患者对他们的健康状况感到满意，而斋月后为34％。禁食之前或之后GERD症状的严重程度与食物类型之间没有关系，吃饭的时机，或消耗的食物量。
结论：结果表明斋月禁食可以改善GERD症状。然而,需要更多的研究来验证这些结果并理解潜在的机制.
方法：这是一项纵向研究，选择GERD患者进行连续采样。患者在两个不同的时间回答问卷：一次在斋月期间，一次在斋月之后。使用经过验证的胃食管反流病健康相关生活质量（GERD-HRQL）自我管理调查。
结果：斋月后，胃灼热症状明显减轻，尤其是躺下的时候。总的来说,45分的胃灼热评分从斋月期间的17.9降至之后的14.3分.反流评分从斋月期间的12.3下降到禁食后的9.9，具有统计学意义(P=0.049)。尽管斋月后满意度要高得多（17%vs.15.1%），差异无统计学意义(P=0.422),斋月期间，45.3％的患者对他们的健康状况感到满意，而斋月后为34％。禁食之前或之后GERD症状的严重程度与食物类型之间没有关系，吃饭的时机，或消耗的食物量。
结论：结果表明斋月禁食可以改善GERD症状。然而,需要更多的研究来验证这些结果并理解潜在的机制.
