关键词: Axial stability Capsulorhexis Cataract Finite element analysis Intraocular lens

Mesh : Capsulorhexis / methods Finite Element Analysis Lens Implantation, Intraocular / methods Lenses, Intraocular Prosthesis Design Humans

来  源:   DOI:10.1016/j.compbiomed.2023.106972

Abstract:
Current treatment of cataract widely used in clinics is by removal of the opacified content from the lens capsule which is followed by insertion of an artificial intraocular lens (IOL). The IOL needs to remain stabilized in the capsular bag for the eye to achieve desired optical quality. The present study aims to investigate how different design parameters of the IOL can influence the axial and rotational stabilities of IOLs using Finite Element Analysis.
Eight designs of IOL with variations in types of optics surface, types of haptics and haptic angulation were constructed using parameters obtained from an online IOL databank (IOLs.eu). Each IOL was subjected to compressional simulations both by two clamps and by a collapsed natural lens capsule with an anterior rhexis. Comparisons were made between the two scenarios on axial displacement, rotation, and distribution of stresses.
The clamps compression method set out by ISO does not always produce the same outcome as the in-the-bag analysis. The open-loop IOLs show better axial stability while the closed-loop IOLs show better rotational stability when compressed by two clamps. Simulations of IOL in the capsular bag only demonstrate better rotational stability for closed-loop designs.
The rotational stability of an IOL is largely dependent on its haptic design whilst the axial stability is affected by the appearance of the rhexis to the anterior capsule which has a major influence on designs with a haptic angulation.
摘要:
背景目前在临床上广泛使用的白内障治疗是通过从晶状体囊中去除不透明的内容物,然后插入人工人工晶状体(IOL)。IOL需要在囊袋中保持稳定以用于眼睛以实现期望的光学质量。本研究旨在研究IOL的不同设计参数如何使用有限元分析影响IOL的轴向和旋转稳定性。
方法:光学表面类型不同的八种IOL设计,使用从在线IOL数据库(IOL。欧盟)。每个IOL都通过两个夹具和带有前撕裂的塌陷的自然晶状体囊进行了压缩模拟。对轴向位移的两种情况进行了比较,旋转,和应力分布。
结果:ISO规定的夹具压缩方法并不总是产生与袋中分析相同的结果。开环IOL显示出更好的轴向稳定性,而闭环IOL在被两个夹具压缩时显示出更好的旋转稳定性。囊袋中IOL的模拟仅证明闭环设计具有更好的旋转稳定性。
结论:人工晶状体的旋转稳定性在很大程度上取决于其触觉设计,而轴向稳定性受前囊的rhexis外观的影响,这对具有触觉角度的设计有重要影响。
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