PDF(Pubmed)
Abstract：
We conducted a systematic review and evidence gap mapping to explore the existing supportive care interventions and their impact on well-being outcomes for melanoma patients and caregivers.
We searched MEDLINE, Embase, Web of Science Index Medicus, CINAHL, Lilacs, CENTRAL (Cochrane Library) and PsycINFO in December 2022, including interventional studies assessing the effectiveness of any supportive care intervention among melanoma patients and/or their caregivers.
Twenty studies were included in this review. These studies consisted of randomised controlled trials (n = 11, 55%), pre-post studies (n = 7, 35%) and quasi-experimental trials (n = 2, 10%). All studies originated from high-income countries and focused primarily on melanoma patients, with no studies identified that focused solely on caregivers. Educational interventions were the most common (n = 7, 35%), followed by psychoeducational interventions (n = 6, 30%) and psychotherapeutic interventions (n = 4, 20%). Nearly all included studies (n = 18, 90%) reported a positive effect of the intervention on the primary outcome of interest; however, most studies (n = 17, 85%) were judged to be at moderate or high risk of bias. Due to heterogeneity of study designs, intervention characteristics and outcome measures, meta-analysis was not conducted.
Supportive care interventions have positive impacts on melanoma patient well-being outcomes, while being acceptable and feasible to conduct. More research is needed regarding supportive care interventions for melanoma caregivers. Future research should focus on eliminating sources of bias through rigorous methodology, with the development of standardised outcome measures for psychosocial outcomes to facilitate future meta-analyses.
We searched MEDLINE, Embase, Web of Science Index Medicus, CINAHL, Lilacs, CENTRAL (Cochrane Library) and PsycINFO in December 2022, including interventional studies assessing the effectiveness of any supportive care intervention among melanoma patients and/or their caregivers.
Twenty studies were included in this review. These studies consisted of randomised controlled trials (n = 11, 55%), pre-post studies (n = 7, 35%) and quasi-experimental trials (n = 2, 10%). All studies originated from high-income countries and focused primarily on melanoma patients, with no studies identified that focused solely on caregivers. Educational interventions were the most common (n = 7, 35%), followed by psychoeducational interventions (n = 6, 30%) and psychotherapeutic interventions (n = 4, 20%). Nearly all included studies (n = 18, 90%) reported a positive effect of the intervention on the primary outcome of interest; however, most studies (n = 17, 85%) were judged to be at moderate or high risk of bias. Due to heterogeneity of study designs, intervention characteristics and outcome measures, meta-analysis was not conducted.
Supportive care interventions have positive impacts on melanoma patient well-being outcomes, while being acceptable and feasible to conduct. More research is needed regarding supportive care interventions for melanoma caregivers. Future research should focus on eliminating sources of bias through rigorous methodology, with the development of standardised outcome measures for psychosocial outcomes to facilitate future meta-analyses.
摘要：
目的：我们进行了系统评价和证据差距图，以探讨现有的支持性护理干预措施及其对黑色素瘤患者和护理人员的健康结局的影响。
方法：我们搜索了MEDLINE，Embase,WebofScienceIndexMedicus,CINAHL,丁香花,CENTRAL（Cochrane图书馆）和PsycINFO于2022年12月发布，包括评估黑色素瘤患者和/或其护理人员中任何支持性护理干预的有效性的介入研究。
结果：本综述纳入了20项研究。这些研究包括随机对照试验（n=11，55%），研究前（n=7，35%）和准实验试验（n=2，10%）。所有研究都来自高收入国家，主要针对黑色素瘤患者，没有研究确定只关注护理人员。教育干预是最常见的(n=7，35%)，其次是心理教育干预（n=6，30％）和心理治疗干预（n=4，20％）。几乎所有纳入的研究（n=18，90％）都报告了干预措施对感兴趣的主要结局的积极影响；然而，大多数研究(n=17,85%)被判断为中度或高度偏倚风险.由于研究设计的异质性，干预特点和结果措施，没有进行荟萃分析。
结论：支持性护理干预对黑色素瘤患者的健康结局有积极影响，同时是可以接受和可行的。需要更多关于对黑色素瘤护理人员的支持性护理干预的研究。未来的研究应该集中在通过严格的方法消除偏见的来源，随着社会心理结果标准化结果测量的发展，以促进未来的荟萃分析。
方法：我们搜索了MEDLINE，Embase,WebofScienceIndexMedicus,CINAHL,丁香花,CENTRAL（Cochrane图书馆）和PsycINFO于2022年12月发布，包括评估黑色素瘤患者和/或其护理人员中任何支持性护理干预的有效性的介入研究。
结果：本综述纳入了20项研究。这些研究包括随机对照试验（n=11，55%），研究前（n=7，35%）和准实验试验（n=2，10%）。所有研究都来自高收入国家，主要针对黑色素瘤患者，没有研究确定只关注护理人员。教育干预是最常见的(n=7，35%)，其次是心理教育干预（n=6，30％）和心理治疗干预（n=4，20％）。几乎所有纳入的研究（n=18，90％）都报告了干预措施对感兴趣的主要结局的积极影响；然而，大多数研究(n=17,85%)被判断为中度或高度偏倚风险.由于研究设计的异质性，干预特点和结果措施，没有进行荟萃分析。
结论：支持性护理干预对黑色素瘤患者的健康结局有积极影响，同时是可以接受和可行的。需要更多关于对黑色素瘤护理人员的支持性护理干预的研究。未来的研究应该集中在通过严格的方法消除偏见的来源，随着社会心理结果标准化结果测量的发展，以促进未来的荟萃分析。
