PDF(Pubmed)
Abstract：
UNASSIGNED: Mammary analogue secretory carcinoma (MASC) is a new disease among tumours affecting the salivary glands. It was first reported in 2010, and few cases have been reported worldwide. MASC is often incorrectly diagnosed as salivary gland acinic cell carcinoma. We present here the case of a patient with an asymptomatic parotid tumour who underwent a parotidectomy of the superficial lobe.
UNASSIGNED: A 78-year-old female patient came to the clinic for a tumour of approximately 2.5 × 2.5 cm and a hard, elastic consistency that had grown insidiously in the right preauricular region. Magnetic resonance imaging of the head and neck showed a heterogeneous ovoid lesion located in the lower part of the superficial lobe of the right parotid gland, measuring 29 × 27 × 27 mm. A superficial parotidectomy was performed with the facial nerve identified and preserved. Immunohistochemistry was positive for S100, mammaglobin, periodic acid Schiff (PAS) and GATA-3. Fluorescence in situ hybridisation analysis was subsequently performed and Translocation-ETS-Leukemia Virus (ETV6) gene rearrangement observed. These findings were consistent with diagnosis of a MASC. The patient then required no new interventions or adjuvant therapy. At publication, she was free of disease and continues in clinical follow-up.
UNASSIGNED: MASC is a tumour of the saliva glands that is recently described and rare. There are no studies that describe its biological behaviour or prognosis precisely.
UNASSIGNED: A 78-year-old female patient came to the clinic for a tumour of approximately 2.5 × 2.5 cm and a hard, elastic consistency that had grown insidiously in the right preauricular region. Magnetic resonance imaging of the head and neck showed a heterogeneous ovoid lesion located in the lower part of the superficial lobe of the right parotid gland, measuring 29 × 27 × 27 mm. A superficial parotidectomy was performed with the facial nerve identified and preserved. Immunohistochemistry was positive for S100, mammaglobin, periodic acid Schiff (PAS) and GATA-3. Fluorescence in situ hybridisation analysis was subsequently performed and Translocation-ETS-Leukemia Virus (ETV6) gene rearrangement observed. These findings were consistent with diagnosis of a MASC. The patient then required no new interventions or adjuvant therapy. At publication, she was free of disease and continues in clinical follow-up.
UNASSIGNED: MASC is a tumour of the saliva glands that is recently described and rare. There are no studies that describe its biological behaviour or prognosis precisely.
摘要：
■乳腺类似物分泌癌（MASC）是影响唾液腺的肿瘤中的一种新疾病。它于2010年首次报告，全世界几乎没有报告病例。MASC经常被错误地诊断为唾液腺腺泡细胞癌。我们在这里介绍一名无症状腮腺肿瘤患者，该患者接受了浅叶腮腺切除术。
一名78岁的女性患者因肿瘤约2.5×2.5厘米而来到诊所，在右耳前区域隐匿生长的弹性稠度。头部和颈部的磁共振成像显示位于右腮腺浅叶下部的异质性卵圆形病变，29×27×27毫米。在识别并保留面神经的情况下进行浅表腮腺切除术。免疫组织化学S100阳性，乳腺球蛋白，高碘酸希夫（PAS）和GATA-3。随后进行荧光原位杂交分析并观察到易位-ETS-白血病病毒(ETV6)基因重排。这些发现与MASC的诊断一致。然后患者不需要新的干预或辅助治疗。在出版时，她没有患病,继续进行临床随访.
■MASC是一种最近被描述且罕见的唾液腺肿瘤。没有准确描述其生物学行为或预后的研究。
一名78岁的女性患者因肿瘤约2.5×2.5厘米而来到诊所，在右耳前区域隐匿生长的弹性稠度。头部和颈部的磁共振成像显示位于右腮腺浅叶下部的异质性卵圆形病变，29×27×27毫米。在识别并保留面神经的情况下进行浅表腮腺切除术。免疫组织化学S100阳性，乳腺球蛋白，高碘酸希夫（PAS）和GATA-3。随后进行荧光原位杂交分析并观察到易位-ETS-白血病病毒(ETV6)基因重排。这些发现与MASC的诊断一致。然后患者不需要新的干预或辅助治疗。在出版时，她没有患病,继续进行临床随访.
■MASC是一种最近被描述且罕见的唾液腺肿瘤。没有准确描述其生物学行为或预后的研究。
