关键词: COVID-19 airborne pathogens co-infections influenza severe acute respiratory infection

来  源:   DOI:10.3390/vaccines11040776   PDF(Pubmed)

Abstract:
Winter in the northern hemisphere is characterized by the circulation of influenza viruses, which cause seasonal epidemics, generally from October to April. Each influenza season has its own pattern, which differs from one year to the next in terms of the first influenza case notification, the period of highest incidence, and the predominant influenza virus subtypes. After the total absence of influenza viruses in the 2020/2021 season, cases of influenza were again recorded in the 2021/2022 season, although they remained below the seasonal average. Moreover, the co-circulation of the influenza virus and the SARS-CoV-2 pandemic virus was also reported. In the context of the DRIVE study, oropharyngeal swabs were collected from 129 Tuscan adults hospitalized for severe acute respiratory infection (SARI) and analyzed by means of real-time polymerase chain reaction (RT-PCR) for SARS-CoV-2 and 21 different airborne pathogens, including influenza viruses. In total, 55 subjects tested positive for COVID-19, 9 tested positive for influenza, and 3 tested positive for both SARS-CoV-2 and the A/H3N2 influenza virus. The co-circulation of different viruses in the population requires strengthened surveillance that is no longer restricted to the winter months. Indeed, constant, year-long monitoring of the trends of these viruses is needed, especially in at-risk groups and elderly people.
摘要:
北半球冬季的特点是流感病毒的流行,导致季节性流行病,一般从10月到4月。每个流感季节都有自己的模式,在第一次流感病例通知方面,从一年到下一年有所不同,发病率最高的时期,和主要的流感病毒亚型。在2020/2021季节完全没有流感病毒之后,在2021/2022年季节再次记录流感病例,尽管它们仍然低于季节性平均水平。此外,还报道了流感病毒和SARS-CoV-2大流行病毒的共同传播。在DRIVE研究的背景下,收集了129例因严重急性呼吸道感染(SARI)住院的托斯卡纳成年人的口咽拭子,并通过实时聚合酶链反应(RT-PCR)分析了SARS-CoV-2和21种不同的空气传播病原体,包括流感病毒。总的来说,55名受试者COVID-19检测呈阳性,9名受试者流感检测呈阳性,3对SARS-CoV-2和A/H3N2流感病毒均呈阳性。不同病毒在人群中的共同传播需要加强监测,不再局限于冬季。的确,常数,需要对这些病毒的趋势进行为期一年的监测,尤其是高危人群和老年人。
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