PDF(Pubmed)
Abstract：
Trichinellosis, a serious and sometimes fatal human disease, is a consequence of consuming raw or improperly cooked meat containing the infective larvae of Trichinella spp. The aim of this observational cohort retrospective study is to compare the epidemiological, laboratory, clinical and therapeutic aspects of trichinellosis in children and adults from Western Romania. We investigated the medical records of patients who were diagnosed with trichinellosis and hospitalized between 17 January 2010 and 31 December 2020. One hundred thirty-three patients were identified according to the electronic databases of infectious disease hospitals, located in four counties from Western Romania. A total of 19 patients (14.28%) were children and 114 patients (85.71%) were adults. In children, the most frequent symptoms were digestive in 78.94%, followed by fever in 57.89%, eyelid or facial edema in 57.89% and myalgia in 52.63% of cases, while adults presented mainly myalgia in 87.71%, followed by fever in 77.19%, digestive symptoms in 68.42% and eyelid or facial edema in 66.66% of cases. The source of infection was pork meat products in the majority of patients (89.47%). Our results revealed a general declining trend in infection rates for both children and adults during the studied period. The vast majority of cases were severe and all required hospitalization. Education of the population along with public health strategies should be improved and maintained to fully prevent trichinellosis in Western Romania.
摘要：
旋毛虫病,一种严重的，有时是致命的人类疾病，是食用含有旋毛虫属感染幼虫的生肉或不适当煮熟的肉的结果。这项观察性队列回顾性研究的目的是比较流行病学，实验室,罗马尼亚西部儿童和成人旋毛虫病的临床和治疗方面。我们调查了2010年1月17日至2020年12月31日期间被诊断为旋毛虫病并住院的患者的医疗记录。根据传染病医院电子数据库确定了一百三十三个病人,位于罗马尼亚西部的四个县。共有19例（14.28%）为儿童，114例（85.71%）为成人。在儿童中，最常见的症状是消化，占78.94%，其次是57.89%的发烧，眼睑或面部水肿占57.89%，肌痛占52.63%，而87.71%的成年人主要表现为肌痛，其次是发烧的77.19%，消化系统症状占68.42%，眼睑或面部水肿占66.66%。大多数患者的感染源是猪肉制品(89.47%)。我们的结果表明，在研究期间，儿童和成人的感染率总体呈下降趋势。绝大多数病例是严重的，都需要住院治疗。应改善和维持人口教育以及公共卫生战略，以充分预防罗马尼亚西部的旋毛虫病。
