关键词: Candida Cryptococcus Malassezia Rhodotorula mycobiome

来  源:   DOI:10.3390/life13040924   PDF(Pubmed)

Abstract:
The microbiome consists mostly of bacteria, but new evidence and developments in sequencing methods have shown that fungi play an important role in human health and in the stability of the microbiota. Scientific knowledge about the role of commensal fungi in intestinal, oral, vaginal and cutaneous communities has been increasing; however, more studies are still needed to better understand their action in these niches. To date, fungal research focuses primarily on opportunistic diseases caused by fungal species, leaving unclear the possible role of fungi as an integral part of the microbiota. Although they are much less abundant than bacteria, fungi such as species belonging to the genus Candida, Malassezia, Rhodotorula and Cryptococcus are some of the yeasts that have been in the focus of the scientific community because they inhabit various niches. In this review, we have summarized the current information about the yeasts that inhabit the human body, including some of the diseases that they can cause when the microbiota becomes unstable.
摘要:
微生物组主要由细菌组成,但是新的证据和测序方法的发展表明,真菌在人类健康和微生物群的稳定性中起着重要作用。有关共生真菌在肠道中的作用的科学知识,口服,阴道和皮肤社区一直在增加;然而,仍需要更多的研究来更好地了解它们在这些利基市场中的作用。迄今为止,真菌研究主要集中在由真菌引起的机会性疾病,不清楚真菌作为微生物群不可或缺的一部分的可能作用。虽然它们比细菌丰富得多,真菌,如属于念珠菌属的物种,马拉色菌,红球菌和隐球菌是科学界关注的一些酵母,因为它们栖息在各种壁龛中。在这次审查中,我们总结了目前关于人类体内酵母的信息,包括当微生物群变得不稳定时它们可能引起的一些疾病。
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