Abstract：
Central vascular access devices (CVADs) are standard for the treatment of leukemia. The objectives of this study were to examine predictors for central line-associated bloodstream infection (CLABSI) and causative microorganisms. A retrospective case/control design was used to examine electronic health records (EHRs) of patients with acute leukemia, a CVAD, and neutropenia. Variables were examined for differences between those who developed bacteremia (cases: n = 10) and those who did not (controls: n = 13). Variables included conditions of health (eg, patient history, laboratory results at the time of nadir, nutritional intake during hospitalization, and CVAD care practices). Fisher exact and Mann-Whitney U tests were used for comparison. Nine organisms were identified, including viridans group streptococci (20%) and Escherichia coli (20%). No statistical differences in variables were found between groups. However, over 50% of the nutritional intake data was missing due to lack of documentation. These findings indicate that further study is needed to examine barriers for electronic documentation. The data collection site found opportunities to improve patient care that included education regarding the daily care of CVADs, collaboration with nutritional services to ensure accurate assessments, and coordination with clinical information systems to improve clinical documentation compliance.
摘要：
中央血管通路装置(CVAD)是治疗白血病的标准。这项研究的目的是检查中心线相关血流感染（CLABSI）和致病微生物的预测因子。回顾性病例/对照设计用于检查急性白血病患者的电子健康记录（EHRs），一个CVAD,和中性粒细胞减少症.检查了发生菌血症的人（病例：n=10）和未发生菌血症的人（对照：n=13）之间的差异。变量包括健康状况(例如，病史,最低点时的实验室结果，住院期间的营养摄入量，和CVAD护理实践)。使用Fisher精确检验和Mann-WhitneyU检验进行比较。确定了九种生物，包括绿柱石群链球菌(20%)和大肠杆菌(20%)。组间变量无统计学差异。然而,由于缺乏文件,超过50%的营养摄入数据缺失.这些发现表明，需要进一步研究以检查电子文档的障碍。数据收集网站发现了改善患者护理的机会，其中包括有关CVAD日常护理的教育，与营养服务部门合作，以确保准确的评估，以及与临床信息系统的协调，以提高临床文档的合规性。
