Abstract：
Transarterial chemoembolization (TACE) is a widely used hepatocellular carcinoma (HCC) treatment. Some cases of supraumbilical skin rash after TACE in patients with HCC have been reported. To the best of the authors\' knowledge, there are no reports on atypical, generalized rashes caused by doxorubicin systemic absorption after TACE. This paper presents the case of a 64-year-old male with HCC who developed generalized macules and patches one day after a successful TACE procedure. A histology examination of a skin biopsy of a dark reddish patch on the knee revealed severe interface dermatitis. He was treated with a topical steroid, and all skin rashes improved within a week with no side effects. This report presents this rare case with a literature review on skin rash after TACE.
摘要：
经动脉化疗栓塞（TACE）是一种广泛使用的肝细胞癌（HCC）治疗方法。已经报道了一些HCC患者TACE后脐上皮疹的病例。据作者所知，没有关于非典型的报道，TACE后阿霉素全身吸收引起的全身性皮疹。本文介绍了一名64岁的男性HCC患者，该患者在成功的TACE手术后一天出现了全身性黄斑和斑块。对膝盖上暗红色斑块的皮肤活检的组织学检查显示出严重的界面皮炎。他接受了局部类固醇治疗，所有皮疹都在一周内得到改善，没有副作用。本报告介绍了这种罕见的病例，并对TACE后皮疹进行了文献综述。
