PDF(Pubmed)
Abstract：
Nephrogenic adenoma is a benign lesion of the urothelial tract characterized by tubules surrounded by thick, hyalinized basement membranes. There is a great variety of architectural patterns within nephrogenic adenomas, including patterns that mimic malignancy, such as focal clear or hobnail cells, areas of significant nuclear atypia, mitosis, and isolated cystic changes. This represents a diagnostic pitfall, where a malignant lesion can be mistaken for a nephrogenic adenoma, leading to a delay in diagnosis and treatment that adversely affects the outcome. In this case report, we describe a nephrogenic adenoma arising in a female urethral diverticulum and discuss the differential diagnosis, which includes clear cell carcinomas, microcystic variant urothelial carcinomas, and Skene\'s gland cysts.
摘要：
肾源性腺瘤是尿路上皮道的良性病变，其特征是小管被厚，透明的基底膜。肾性腺瘤中有各种各样的建筑模式，包括模仿恶性肿瘤的模式，例如局灶性透明细胞或Hobnail细胞，严重的核非典型区域，有丝分裂,和孤立的囊性改变。这是一个诊断缺陷，恶性病变可以被误认为是肾性腺瘤，导致诊断和治疗延迟，对结果产生不利影响。在这个案例报告中,我们描述了女性尿道憩室中出现的肾源性腺瘤，并讨论了鉴别诊断，包括透明细胞癌，微囊变异型尿路上皮癌，和Skene的腺体囊肿.
