PDF(Pubmed)
Abstract：
UNASSIGNED: The aim of the current study was to evaluate the antioxidant effect, acetylcholinesterase (AChE) inhibitory effect and phytochemical screening of different extracts of aerial root extract of Ficus benghalensis using in-vitro methods.
UNASSIGNED: The aerial root extract was prepared by successive extraction method using different organic solvents having increasing order of polarity. FB aerial root extract was screened for preliminary phytochemical analysis. FB aerial root extracts were evaluated for in-vitro acetylcholinesterase inhibitory effect by the Ellman\'s method and anti-oxidant potential by DPPH assay and hydroxyl radical neutralizing assay.
UNASSIGNED: Preliminary phytochemical screening of FB extracts indicate the existence of the phytochemicals such as phenols, alkaloids, flavonoids, glycosides, anthraquinones, tannins and steroids. The results of the DPPH assay, hydroxyl radical scavenging assay and AChE inhibitory assay show that chloroform and ethyl acetate extracts are having significant antioxidant activity and acetylcholinesterase inhibitory effect as compared to the other extracts, respectively.
UNASSIGNED: The results of the current study suggest that the aerial root extract of FB might be a potential drug source for treatment of neurodegenerative disorders like Alzheimer disease.
UNASSIGNED: The aerial root extract was prepared by successive extraction method using different organic solvents having increasing order of polarity. FB aerial root extract was screened for preliminary phytochemical analysis. FB aerial root extracts were evaluated for in-vitro acetylcholinesterase inhibitory effect by the Ellman\'s method and anti-oxidant potential by DPPH assay and hydroxyl radical neutralizing assay.
UNASSIGNED: Preliminary phytochemical screening of FB extracts indicate the existence of the phytochemicals such as phenols, alkaloids, flavonoids, glycosides, anthraquinones, tannins and steroids. The results of the DPPH assay, hydroxyl radical scavenging assay and AChE inhibitory assay show that chloroform and ethyl acetate extracts are having significant antioxidant activity and acetylcholinesterase inhibitory effect as compared to the other extracts, respectively.
UNASSIGNED: The results of the current study suggest that the aerial root extract of FB might be a potential drug source for treatment of neurodegenerative disorders like Alzheimer disease.
摘要：
■当前研究的目的是评估抗氧化作用，采用体外方法对无花果地上根提取物的乙酰胆碱酯酶（AChE）抑制作用及植物化学筛选。
■通过使用极性顺序递增的不同有机溶剂的连续提取方法制备气生根提取物。筛选FB气生根提取物用于初步的植物化学分析。通过Ellman方法评估了FB气生根提取物的体外乙酰胆碱酯酶抑制作用，并通过DPPH测定法和羟基自由基中和测定法评估了抗氧化潜力。
■FB提取物的初步植物化学筛选表明存在植物化学物质，例如酚类，生物碱，黄酮类化合物，糖苷，蒽醌,单宁和类固醇。DPPH测定的结果，羟自由基清除试验和AChE抑制试验表明，氯仿和乙酸乙酯提取物与其他提取物相比具有显著的抗氧化活性和乙酰胆碱酯酶抑制作用，分别。
■当前研究的结果表明，FB的地上根提取物可能是治疗神经退行性疾病如阿尔茨海默病的潜在药物来源。
■通过使用极性顺序递增的不同有机溶剂的连续提取方法制备气生根提取物。筛选FB气生根提取物用于初步的植物化学分析。通过Ellman方法评估了FB气生根提取物的体外乙酰胆碱酯酶抑制作用，并通过DPPH测定法和羟基自由基中和测定法评估了抗氧化潜力。
■FB提取物的初步植物化学筛选表明存在植物化学物质，例如酚类，生物碱，黄酮类化合物，糖苷，蒽醌,单宁和类固醇。DPPH测定的结果，羟自由基清除试验和AChE抑制试验表明，氯仿和乙酸乙酯提取物与其他提取物相比具有显著的抗氧化活性和乙酰胆碱酯酶抑制作用，分别。
■当前研究的结果表明，FB的地上根提取物可能是治疗神经退行性疾病如阿尔茨海默病的潜在药物来源。
