PDF(Pubmed)
Abstract：
Pulmonary nodular lymphoid hyperplasia (PNLH) is a rare non-neoplastic disease that presents with mass lesions in the lung. It is radiologically difficult to differentiate it from adenocarcinoma of the lung or pulmonary lymphoma. There has been no consensus regarding the treatment of PNLH; however, in many case series, patients usually undergo surgical resection for diagnostic and therapeutic purposes. Here, we present the case of a 60-year-old Chinese male who presented with cough and hemoptysis. A computed tomography scan of the thorax revealed a mass-like lesion. A biopsy was performed which showed lymphocytic pneumonitis. He was treated with a tapering dose of corticosteroids with good clinical and radiological outcomes. Upon a subsequent review of the case, a diagnosis of PNLH was made. This case report suggests that corticosteroids may be an alternative therapy to surgical resection. They have the advantage of being non-invasive and can be used in patients who are otherwise not surgical candidates due to other comorbidities. However, further research is required before we can recommend corticosteroids as a treatment for PNLH.
摘要：
肺结节性淋巴样增生（PNLH）是一种罕见的非肿瘤性疾病，表现为肺部肿块病变。放射学难以将其与肺腺癌或肺淋巴瘤区分开。关于PNLH的治疗尚未达成共识；然而，在许多案例系列中，患者通常接受手术切除以达到诊断和治疗目的。这里,我们介绍了一名60岁的中国男性，他表现为咳嗽和咯血。胸部计算机断层扫描显示肿块状病变。进行活检，显示淋巴细胞性肺炎。他接受了逐渐减少剂量的皮质类固醇治疗，临床和放射学结果良好。在随后对案件进行审查后，诊断为PNLH.此病例报告表明，皮质类固醇可能是手术切除的替代疗法。它们具有非侵入性的优点，并且可以用于由于其他合并症而不是手术候选人的患者。然而,在我们推荐使用皮质类固醇作为PNLH的治疗方法之前,还需要进一步的研究.
