PDF(Pubmed)
Abstract：
UNASSIGNED: Conjunctival papilloma commonly develops in infants and children. It is believed that the etiologic agent, human papillomavirus (HPV), gets implanted from the infected maternal birth canal in the conjunctival sac of the new borne while parturition. It grows as solitary or multiple pedunculated benign masses adjacent to the caruncle. It is uncommon but if growing in adults it grows on the limbal conjunctiva and could be malignant.
UNASSIGNED: An Afro-American adult male developed two distinct conjunctival growths on his left lower lid. One growth was pedunculated and the second one sessile. The initial diagnosis of \'benign conjunctival papillomas\' was made. Patient was recommended to wait and watch. After about two years the neoplasia had doubled their sizes. Surgical excisional biopsy was performed for diagnostic and therapeutic reasons. The tumor beds were treated with intra-operative cryotherapy using liquid nitrogen and applying double-freeze-thaw technique. Histopathology proved the masses to be benign and caused by HPV. Recurrence and seeding of virus during surgical excision leading to multiple new masses are dreaded complications during management of conjunctival papilloma. Though a short follow-up, yet after three months there were no signs of recurrence.
UNASSIGNED: A brief review of literature is presented to highlight the fact that rarely such conjunctival papillomas may develop at unusual sites and in adults. We believe that the uncommon demographic and anatomic presentation of this case is worth sharing with ophthalmic community.
UNASSIGNED: An Afro-American adult male developed two distinct conjunctival growths on his left lower lid. One growth was pedunculated and the second one sessile. The initial diagnosis of \'benign conjunctival papillomas\' was made. Patient was recommended to wait and watch. After about two years the neoplasia had doubled their sizes. Surgical excisional biopsy was performed for diagnostic and therapeutic reasons. The tumor beds were treated with intra-operative cryotherapy using liquid nitrogen and applying double-freeze-thaw technique. Histopathology proved the masses to be benign and caused by HPV. Recurrence and seeding of virus during surgical excision leading to multiple new masses are dreaded complications during management of conjunctival papilloma. Though a short follow-up, yet after three months there were no signs of recurrence.
UNASSIGNED: A brief review of literature is presented to highlight the fact that rarely such conjunctival papillomas may develop at unusual sites and in adults. We believe that the uncommon demographic and anatomic presentation of this case is worth sharing with ophthalmic community.
摘要：
■结膜乳头状瘤通常发生在婴儿和儿童中。据信病原体，人乳头瘤病毒（HPV），在分娩时从受感染的产妇产道植入新出生的结膜囊。它生长为单生或多个有花梗的良性肿块，与节状相邻。这是不常见的，但如果在成人中生长，它会在结膜角膜缘生长，可能是恶性的。
■一名美国黑人成年男性在其左下眼睑出现两种明显的结膜生长。一个生长被花梗，第二个生长被固着。最初诊断为“良性结膜乳头状瘤”。建议患者等待观察。大约两年后，肿瘤的大小增加了一倍。出于诊断和治疗原因，进行了手术切除活检。使用液氮并应用双冻融技术对瘤床进行术中冷冻治疗。组织病理学证明肿块是良性的，由HPV引起。手术切除期间病毒的复发和播种导致多个新肿块是结膜乳头状瘤治疗期间的可怕并发症。尽管是短暂的后续行动，然而三个月后没有复发的迹象.
■对文献的简要回顾强调了这样一个事实，即很少有结膜乳头状瘤可以在不寻常的部位和成人中发展。我们认为，这种病例的罕见人口统计学和解剖学表现值得与眼科社区分享。
■一名美国黑人成年男性在其左下眼睑出现两种明显的结膜生长。一个生长被花梗，第二个生长被固着。最初诊断为“良性结膜乳头状瘤”。建议患者等待观察。大约两年后，肿瘤的大小增加了一倍。出于诊断和治疗原因，进行了手术切除活检。使用液氮并应用双冻融技术对瘤床进行术中冷冻治疗。组织病理学证明肿块是良性的，由HPV引起。手术切除期间病毒的复发和播种导致多个新肿块是结膜乳头状瘤治疗期间的可怕并发症。尽管是短暂的后续行动，然而三个月后没有复发的迹象.
■对文献的简要回顾强调了这样一个事实，即很少有结膜乳头状瘤可以在不寻常的部位和成人中发展。我们认为，这种病例的罕见人口统计学和解剖学表现值得与眼科社区分享。
