PDF(Pubmed)
Abstract：
Ameloblastic fibroma is a rare mixed odontogenic benign tumor that can occur in either mandible or maxilla but mostly it is found in posterior region of mandible. It can present either peripherally or centrally with a majority of the cases predominantly occurring in first two decades of life and mostly affects male patients. It is characterized by epithelial islands and cords submerged in ectomesenchyme that bear resemblance to the dental papilla and enamel organ but without actual hard tissue formation. Ameloblastic fibroma is a rare odontogenic tumor consisting of neoplastic epithelial and mesenchymal tissues. Recent reports have suggested that this lesion has the potential for high recurrence (18%) and greater chances of recurrent Ameloblastic fibroma transforming into Ameloblastic fibrosarcoma (45%). A 34-year-old male patient presented with pain and swelling in right mandibular posterior region. Intraorally expansion of buccal cortical plate with tenderness over swelling was present. Extraoral examination revealed facial asymmetry on right side. In view of imaging and clinical findings, provisional diagnosis of Odontogenic Keratocyst or Recurrent Ameloblastoma was considered. After obtaining informed consent and general systemic evaluation, the lesion was enucleated under general anesthesia and biopsied which confirmed the diagnosis of Ameloblastic fibroma. Ameloblastic fibroma is a mixed odontogenic tumor composed of odontogenic ectomesenchyme resembling dental papilla with epithelial strands and nests similar to the dental lamina and enamel organ, but with no dental hard tissue formation. Odontogenic tumors, Ameloblasts, Ameloblastoma, Jaw neoplasm.
摘要：
成釉细胞纤维瘤是一种罕见的混合牙源性良性肿瘤，可发生在下颌骨或上颌骨，但大多数发生在下颌骨的后部。它可以在外周或中心出现，大多数病例主要发生在生命的前二十年，并且主要影响男性患者。其特征是上皮岛和线浸没在外植体中，与牙乳头和釉质器官相似，但没有实际的硬组织形成。成釉细胞纤维瘤是一种罕见的牙源性肿瘤，由上皮和间质组织组成。最近的报道表明，该病变具有高复发率（18％）和复发性成釉细胞纤维瘤转化为成釉细胞纤维肉瘤的可能性更大（45％）。一名34岁的男性患者出现右下颌后部区域疼痛和肿胀。存在口腔内扩张的颊皮质板，肿胀压痛。口外检查显示右侧面部不对称。鉴于影像学和临床表现，考虑牙源性角化囊肿或复发性成釉细胞瘤的临时诊断。在获得知情同意和一般系统评估后，在全身麻醉下摘除病灶，并进行活检，证实诊断为成釉细胞性纤维瘤。成釉细胞纤维瘤是一种混合的牙源性肿瘤，由牙源性外植体组成，类似于牙乳头，上皮链和巢类似于牙层和釉质器官，但没有牙齿硬组织形成。牙源性肿瘤，成虫，成釉细胞瘤,颌骨肿瘤。
