PDF(Pubmed)
Abstract：
Calcifying odontogenic cyst (COC) or Gorlin\'s cyst categorized as a distinct entity by Gorlin et al. in 1962. It is a rare benign developmental cystic lesion that accounts for less than 1% of all odontogenic cysts. It can occur in association with various types of odontogenic tumors such as odontomas. COC is a hybrid lesion of the jaw presenting a manifold variety of clinical behaviors and histopathological characteristics including cystic, solid (neoplastic), and aggressive forms. COC exhibits diversity in terms of its clinical presentations, histopathologic features, and biological behavior. Normally, it presents as asymptomatic, slow developing lesion affecting the maxilla and mandible equally with strong predilection for the anterior segment. Radiographically, these lesions usually present as a unilocular, well-defined radiolucency with radiopaque structures within the lesion, either as irregular calcifications or tooth-like densities. The distinct features of COC as solid or cystic lesions presents with an ameloblastomous component admixed with varying proportions of ghost cells and spherical calcifications. Here, we report an article of calcifying odontogenic cyst associated with compound odontoma in a young patient with lesion in the anterior mandible with review of the various terminologies and classification and histopathology.
摘要：
钙化性牙源性囊肿（COC）或Gorlin囊肿被Gorlin等人归类为一个独特的实体。1962年。这是一种罕见的良性发育性囊性病变，占所有牙源性囊肿的不到1％。它可以与各种类型的牙源性肿瘤如牙瘤相关。COC是颌骨的混合病变，表现出多种临床行为和组织病理学特征，包括囊性，固体（肿瘤），和侵略性的形式。COC在临床表现方面表现出多样性，组织病理学特征,和生物学行为。通常,它表现为无症状，缓慢发展的病变影响上颌骨和下颌骨，对前段有强烈的好感。射线照相,这些病变通常表现为单眼，病灶内具有不透射线结构的明确的射线可透性，不规则钙化或牙齿状密度。COC的明显特征是固体或囊性病变，表现为成釉细胞成分，并混合了不同比例的鬼细胞和球形钙化。这里,我们报道了一篇关于牙源性钙化囊肿与复合牙瘤相关的年轻患者的前下颌骨病变，并回顾了各种术语，分类和组织病理学。
