Abstract:
Neurofibromas are frequently present in the skin, but are uncommon in the oral and maxillofacial region. There are three histological variants of neurofibroma: localized, diffuse, and plexiform. The plexiform histological variant of neurofibroma is the least common and is a rare occurrence in the oral cavity. Furthermore, plexiform neurofibroma is usually pathognomonic of neurofibromatosis type 1. A case of solitary plexiform neurofibroma of the tongue with no evidence of neurofibromatosis in a 50-year-old female Chinese patient is reported here. The lesion presented as a single, large, well-circumscribed rounded mass in the left hemi-tongue. The tumour was completely excised. No recurrence was observed at the 6-month follow-up.
摘要:
神经纤维瘤经常出现在皮肤中,但在口腔颌面部并不常见。神经纤维瘤有三种组织学变异:局部,弥漫,和丛状。神经纤维瘤的丛状组织学变异是最不常见的,在口腔中很少见。此外,丛状神经纤维瘤通常是1型神经纤维瘤病的病理标志。据报道,一名50岁的中国女性患者患有单发的舌头丛状神经纤维瘤,没有神经纤维瘤病的证据。病变呈现为单个,大,左半舌有界限的圆形肿块。肿瘤被完全切除。在6个月的随访中没有观察到复发。