Abstract：
Acute basilar artery occlusion (ABAO) accounts for 1% of all ischemic stroke cases, but has a high rate of severe complications and mortality (75-91%). Intracranial atherosclerosis is an significant cause of ischemic stroke. Revascularization using stents has shown good efficacy. However, intra-stent thrombosis and in-stent restenosis (ISR) are significant complications following stent placement. Drug-coated balloons (DCB), coated with the anti-proliferative drug paclitaxel (an inhibitor of endothelial proliferation), can prevent in-stent restenosis. Successful use of DCB dilation in the coronary and lower extremity vasculature has been reported. In our case, a 68-year-old Chinese male with ABAO was successfully revascularized by DCB dilation and showed dramatic improvement in stroke symptoms. This report may inform future treatment of patients with ABAO.
摘要：
急性基底动脉闭塞（ABAO）占所有缺血性卒中病例的1%，但是严重并发症和死亡率很高（75-91％）。颅内动脉粥样硬化是缺血性卒中的重要原因。使用支架的血运重建显示出良好的疗效。然而,支架内血栓形成和支架内再狭窄(ISR)是支架置入后的重要并发症.药物涂层球囊（DCB），涂有抗增殖药物紫杉醇（内皮增殖抑制剂），可以防止支架内再狭窄。已经报道了在冠状动脉和下肢血管系统中成功使用DCB扩张。在我们的案例中,一名68岁的中国男性ABAO患者通过DCB扩张术成功进行了血运重建,卒中症状显著改善.该报告可能为ABAO患者的未来治疗提供信息。
