Abstract：
OBJECTIVE: To analyze the prescribing trends over a 7-years period, between 2013 and 2020, in a tertiary hospital (Hospital Clinico San Carlos, Madrid, Spain) and its health area.
METHODS: A retrospective study on the data collected from the information systems, \"farm@web\" and \"Farmadrid\", of glaucoma prescriptions in the framework of a public health system (Spanish National Health System) during the last seven years.
RESULTS: Prostaglandin analogues were the most commonly used drugs in monotherapy during the study period (range: 36.82% - 47.07%). Fixed combinations of topical hypotensives had an upward trend since 2013 (range: 39.99% - 54.21%), becoming the most dispensed drugs in 2020 (48.99%). Preservative-free eye drops (lacking benzalkonium chloride, BAK) have displaced preservative containing topical treatments in all pharmacological groups. In 2013, BAK-preserved eye drops accounted for 91.1% of the total prescriptions, however in 2020 they only accounted for 34.2% of total prescriptions.
CONCLUSIONS: The results of the present study highlight the current trend to avoid BAK-preserved eye drops for the treatment of glaucoma.
METHODS: A retrospective study on the data collected from the information systems, \"farm@web\" and \"Farmadrid\", of glaucoma prescriptions in the framework of a public health system (Spanish National Health System) during the last seven years.
RESULTS: Prostaglandin analogues were the most commonly used drugs in monotherapy during the study period (range: 36.82% - 47.07%). Fixed combinations of topical hypotensives had an upward trend since 2013 (range: 39.99% - 54.21%), becoming the most dispensed drugs in 2020 (48.99%). Preservative-free eye drops (lacking benzalkonium chloride, BAK) have displaced preservative containing topical treatments in all pharmacological groups. In 2013, BAK-preserved eye drops accounted for 91.1% of the total prescriptions, however in 2020 they only accounted for 34.2% of total prescriptions.
CONCLUSIONS: The results of the present study highlight the current trend to avoid BAK-preserved eye drops for the treatment of glaucoma.
摘要：
目的：分析7年的处方趋势，2013年至2020年，在一家三级医院(医院诊所圣卡洛斯，马德里,西班牙）及其健康领域。
方法：对从信息系统收集的数据进行回顾性研究，\"farm@web\"和\"Farmadrid\",在过去的七年中，公共卫生系统（西班牙国家卫生系统）框架内的青光眼处方。
结果：前列腺素类似物是研究期间单药治疗中最常用的药物（范围：36.82%-47.07%）。局部降压药的固定组合自2013年以来呈上升趋势（范围：39.99%-54.21%），成为2020年配药最多的药品（48.99%）。无防腐剂滴眼液（缺乏苯扎氯铵，BAK）在所有药理组中都取代了含有局部治疗的防腐剂。2013年,BAK保存的滴眼液占总处方的91.1%,然而，在2020年，它们仅占总处方的34.2%。
结论：本研究的结果强调了目前避免使用BAK保留的滴眼液治疗青光眼的趋势。
方法：对从信息系统收集的数据进行回顾性研究，\"farm@web\"和\"Farmadrid\",在过去的七年中，公共卫生系统（西班牙国家卫生系统）框架内的青光眼处方。
结果：前列腺素类似物是研究期间单药治疗中最常用的药物（范围：36.82%-47.07%）。局部降压药的固定组合自2013年以来呈上升趋势（范围：39.99%-54.21%），成为2020年配药最多的药品（48.99%）。无防腐剂滴眼液（缺乏苯扎氯铵，BAK）在所有药理组中都取代了含有局部治疗的防腐剂。2013年,BAK保存的滴眼液占总处方的91.1%,然而，在2020年，它们仅占总处方的34.2%。
结论：本研究的结果强调了目前避免使用BAK保留的滴眼液治疗青光眼的趋势。
