Mesh : Humans Female Aged Carcinoma, Medullary / pathology surgery Colonic Neoplasms / drug therapy surgery diagnosis Colon, Transverse / surgery pathology Carcinoma, Neuroendocrine / surgery Colectomy

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Abstract:
The patient is a 79-year-old woman who visited her local doctor with a chief complaint of abdominal pain. A lower gastrointestinal endoscopy revealed a circumferential type 3 mass in the transverse colon. The patient was diagnosed with transverse colon cancer (cT3N0M0, cStage Ⅱa)and underwent laparoscopic transverse colectomy(D3). The postoperative course was good, and she was discharged on POD 9. Pathological results showed a diagnosis of medullary carcinoma(pT3N0M0, pStage Ⅱa)with MSI-high. The patient was treated with UFT/UZEL for 6 months as postoperative adjuvant chemotherapy. The patient has been recurrence-free for 1 year and 6 months postoperatively and is under outpatient follow-up. Medullary carcinoma is a rare histologic type that is estimated to account for 2-3% of all colorectal cancers. Medullary carcinoma of the colon is more common in elderly patients, women, and the right side of the colon, with a relatively favorable prognosis. We report a case of medullary carcinoma of the transverse colon in which the patient had a relatively long survival, with some discussion of the literature.
摘要:
患者是一名79岁的妇女,主诉腹痛,到当地医生就诊。下胃肠内窥镜检查显示横结肠有3型周围肿块。患者诊断为横结肠癌(cT3N0M0,cStageⅡa),行腹腔镜横结肠切除术(D3)。术后病程良好,她在9号POD出院了.病理诊断为髓样癌(pT3N0M0,pStageⅡa),MSI高。患者接受UFT/UZEL治疗6个月作为术后辅助化疗。患者术后1年6个月无复发,正在门诊随访。髓样癌是一种罕见的组织学类型,估计占所有结直肠癌的2-3%。结肠髓样癌多见于老年患者,女人,和结肠的右侧,预后相对良好。我们报告了一例横结肠髓样癌,该患者的生存期相对较长,一些文献的讨论。
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